Mortality due to dapsone hypersensitivity syndrome complicating multi-drug therapy for leprosy in Nepal

Mortality due to dapsone hypersensitivity syndrome complicating multi-drug therapy for leprosy in Nepal
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DOI:
10.1258/004947507781524700
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发表时间:
2007-07-01
期刊:
影响因子:
0.6
通讯作者:
Walker, S. L.
Walker, S. L.
中科院分区:
医学4区
文献类型:
--
作者:
Pandey, B.;Shrestha, K.;Walker, S. L.

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氨苯砜是治疗所有类型麻风病的多药疗法的一个组成部分。众所周知,氨苯砜超敏反应综合征(DHS)的治疗复杂化的患者的比例,我们进行了一项回顾性研究的患者开始在1990年和2006年之间的MDT; 2%的开发DHS和0.25%死于DHS。
Dapsone is a component of multi-drug therapy (MDT) for the treatment of all types of leprosy. It is known that dapsone hypersensitivity syndrome (DHS) complicates the treatment in a proportion of patients.We performed a retrospective study of patients commenced on MDT between 1990 and 2006; 2% developed DHS and 0.25% died due to DHS.