EFFECT OF CAGE POPULATION-DENSITY ON PLASMA-CORTICOSTERONE AND PERIPHERAL LYMPHOCYTE POPULATIONS OF LABORATORY MICE
EFFECT OF CAGE POPULATION-DENSITY ON PLASMA-CORTICOSTERONE AND PERIPHERAL LYMPHOCYTE POPULATIONS OF LABORATORY MICE
复制标题
DOI：
10.1258/002367789780746042
复制
发表时间：
1989-10-01
影响因子：
2.4
通讯作者：
OHLSSONWILHELM, BM
中科院分区：
文献类型：
--
作者：
PENG, X;LANG, CM;OHLSSONWILHELM, BM
本文研究了不同鼠笼密度对血浆皮质酮、外周血淋巴细胞及特异性淋巴细胞亚群的影响。将动物以每笼2、4或8只小鼠的组饲养，并在第1、7和14天从这些组的每只动物中采集血样。8只/笼组在第1天和第7天血浆皮质酮浓度显著高于2只或4只/笼组（P < 0.05）。2组外周血淋巴细胞数明显减少（P
The effect of different population densities of mice per cage on plasma corticosterone, peripheral lymphocytes and specific lymphocyte subpopulations was investigated. The animals were housed in groups of 2,4, or 8 mice per cage and the blood samples were taken from each animal of these groups on days one, 7 and 14. A significant elevation (P < 0.05) in plasma corticosterone concentration was observed in the group of 8 mice per cage on days one and 7 as compared with those of 2 or 4 mice per cage. The number of peripheral lymphocytes was significantly decreased in the groups of 2 (P