Potential of Activin B as a Clinical Biomarker in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS).
Potential of Activin B as a Clinical Biomarker in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS).
复制标题
活化素B作为肌力脑脊髓炎/慢性疲劳综合征（ME/CFS）的临床生物标志物的潜力。
DOI：
10.3390/biom11081189
复制
发表时间：
2021-08-11
期刊：
影响因子：
5.5
通讯作者：
Murovska M
中科院分区：
文献类型：
--
作者：
Gravelsina S;Nora-Krukle Z;Vilmane A;Svirskis S;Vecvagare K;Krumina A;Murovska M
Reliable serum biomarkers are of immense need for diagnostic purposes of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS)—a disabling and complex disease for which diagnosis is mainly based on clinical symptoms. The aim of this study was to evaluate a possible diagnostic potential of activin B by directly comparing 134 cases of ME/CFS with 54 healthy controls. Analyses of human activin B level in plasma samples were performed using a validated human activin B ELISA assay. The results of the study show that activin B levels did not differ statistically significantly between ME/CFS patients and healthy controls (p = 0.6511). No gender or age-related differences in activin B levels were observed in the ME/CFS group and healthy controls. The level of activin B tended to decrease with increasing visual analogue scale score (r = −0.2004; p = 0.5085) nevertheless the results obtained so far does not support the clinical utility of activin B as a biomarker for ME/CFS.
登录
查看更多内容
影响因子：
4.1
作者：
Jones, KL;de Kretser, DM;Phillips, DJ
通讯作者：
Phillips, DJ
影响因子：
5.8
作者：
ROBERTS, VJ;BARTH, S;YEN, SSC
通讯作者：
YEN, SSC
影响因子：
4
作者：
Antsiferova, Maria;Werner, Sabine
通讯作者：
Werner, Sabine
DOI：
10.3390/medicina57050510
发表时间：
2021-05-19
期刊：
Medicina (Kaunas, Lithuania)
影响因子：
--
作者：
Nacul L;Authier FJ;Scheibenbogen C;Lorusso L;Helland IB;Martin JA;Sirbu CA;Mengshoel AM;Polo O;Behrends U;Nielsen H;Grabowski P;Sekulic S;Sepulveda N;Estévez-López F;Zalewski P;Pheby DFH;Castro-Marrero J;Sakkas GK;Capelli E;Brundsdlund I;Cullinan J;Krumina A;Bergquist J;Murovska M;Vermuelen RCW;Lacerda EM
通讯作者：
Lacerda EM
影响因子：
1.3
作者：
Minnock, Patricia;Ringner, Anders;McKee, Gabrielle
通讯作者：
McKee, Gabrielle