Preterm Birth and Social Support during Pregnancy: a Systematic Review and Meta-Analysis

Preterm Birth and Social Support during Pregnancy: a Systematic Review and Meta-Analysis
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DOI:
10.1111/ppe.12225
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发表时间:
2015-11-01
影响因子:
2.8
通讯作者:
Sauve, Reg S.
Sauve, Reg S.
中科院分区:
医学3区
文献类型:
--
作者:
Hetherington, Erin;Doktorchik, Chelsea;Sauve, Reg S.

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背景通常建议在产前期间为妇女提供额外的社会支持,以优化分娩结局,特别是避免早产。社会支持被认为是两种方式之一:通过减少压力和焦虑,或通过为高压力的妇女提供应对机制。然而,这方面的证据好坏参半。本荟萃分析的目的是确定低水平的社会支持是否与早产风险增加有关。MethodsSix数据库进行了随机对照试验和队列研究,社会支持和早产没有限制的日期或语言。纳入标准包括使用一个有效的工具来衡量社会支持,并在高收入或中高收入countries.ResultsThere进行的研究检索到的3467条记录,其中16条符合纳入标准。8项研究(n=14630例受试者)显示,与高社会支持相比,低社会支持女性早产的合并比值比(OR)为1.22(95% CI 0.84,1.76)。在高压力水平的女性中,两项研究(n=6374例受试者)得出的合并OR为1.52(95% CI 1.18,1.97)。六项研究的结果不能汇总由于不兼容的结果measurements.ConclusionsThere是没有证据表明社会支持和早产之间的直接关联。然而,社会支持可以在压力和早产之间提供缓冲机制。
BackgroundAdditional social support is often recommended for women during the prenatal period to optimise birth outcomes, specifically to avoid preterm birth. Social support is thought to act in one of two ways: by reducing stress and anxiety, or by providing coping mechanisms for women with high stress. However, evidence in this area is mixed. The purpose of this meta-analysis is to determine if low levels of social support are associated with an increased risk for preterm birth.MethodsSix databases were searched for randomised control trials and cohort studies regarding social support and preterm birth with no limits set on date or language. Inclusion criteria included the use of a validated instrument to measure social support, and studies conducted in high-income or high-middle-income countries.ResultsThere were 3467 records retrieved, 16 of which met the inclusion criteria. Eight studies (n=14630 subjects) demonstrated a pooled odds ratio (OR) of 1.22 (95% CI 0.84, 1.76) for preterm birth in women with low social support compared with high social support. Among women with high stress levels, two studies (n=6374 subjects) yielded a pooled OR of 1.52 (95% CI 1.18, 1.97). The results of six studies could not be pooled due to incompatibility of outcome measures.ConclusionsThere is no evidence for a direct association between social support and preterm birth. Social support, however, may provide a buffering mechanism between stress and preterm birth.