Large-scale production of oligosaccharides using engineered bacteria
Large-scale production of oligosaccharides using engineered bacteria
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DOI：
10.1016/s0959-440x(00)00127-5
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发表时间：
2000-10-01
影响因子：
6.8
通讯作者：
Koizumi, S
中科院分区：
文献类型：
--
作者：
Endo, T;Koizumi, S
糖基转移酶基因（尤其是细菌中的糖基转移酶基因）的克隆和表达的快速进展，可能为克服寡糖大规模生产中的困难开辟道路。使用从工程微生物或全细胞中分离的糖基转移酶作为酶源大规模生产寡糖可能会推动碳水化合物合成领域的新纪元。
Rapid advances in the cloning and expression of glycosyltransferase genes, especially from bacteria, could open the way to overcoming difficulties in the mass production of oligosaccharides. The large-scale production of oligosaccharides using either glycosyltransferases isolated from engineered microorganisms or whole cells as an enzyme source could promote a new era in the field of carbohydrate synthesis.