Prevalence of dental caries and periodontal disease in patients with inflammatory bowel disease:: a case-control study
Prevalence of dental caries and periodontal disease in patients with inflammatory bowel disease:: a case-control study
复制标题
DOI：
10.1111/j.1600-051x.2006.00942.x
复制
发表时间：
2006-07-01
影响因子：
6.7
通讯作者：
Jepsen, Soren
中科院分区：
文献类型：
--
作者：
Groessner-Schreiber, Birte;Fetter, Thomas;Jepsen, Soren
目的：先前的研究表明炎症性肠病（IBD）患者的龋齿发病率较高，IBD和牙周炎的免疫发病机制相似。本研究评估了IBD患者的牙周病和龋齿患病率。方法：在本病例对照研究中，对62名寻求治疗的IBD患者和59名牙科诊所的匹配健康对照进行了临床检查。口腔软组织的改变，龋坏，缺失和填充的牙齿表面（DMF-S）指数，牙本质龋，菌斑指数（PI），探诊出血（BOP），探诊袋深度（PPD）和临床附着丧失（CAL）进行了评价，在每个病人和对照组。DMF-S指数没有显示出显著差异，但IBD患者中牙本质龋的受试者数量显著较高。IBD患者的平均PPD为2.08 mm，对照组为2.23 mm（p=0.014）。与对照组相比，IBD患者有更多的网站CAL至少4毫米（81%与64%的对照组，p=0.07）和5毫米（63%与46%，p=0.07），分别：本病例对照研究的结果表明，IBD患者的牙本质龋的频率较高，但牙周调查结果显示，没有明显的差异，病例和对照组之间。
Aim: Previous reports suggest a higher incidence of dental caries in patients with inflammatory bowel disease (IBD) and similarities in the immunopathogenesis of IBD and periodontitis. This study assessed the prevalence of periodontal disease and caries in patients with IBD.Methods: In the present case-control study, 62 patients seeking treatment of IBD and 59 matched healthy controls of a dental practice were clinically examined. Oral soft-tissue alterations, the decayed, missing and filled tooth surface (DMF-S) index, dentine caries, plaque index (PI), bleeding on probing (BOP), probing pocket depth (PPD) and clinical attachment loss (CAL) were evaluated in each patient and in the controls.Results: Patients with IBD showed a significantly higher number of oral manifestations compared with controls. The DMF-S index showed no significant differences, but there was a significantly higher number of subjects with dentine caries in patients with IBD. The mean PPD in patients with IBD was 2.08 versus 2.23 mm in controls (p=0.014). Compared with controls, patients with IBD had more sites with CAL of at least 4 mm (81% versus 64% in controls, p=0.07) and 5 mm (63% versus 46%, p=0.07), respectively.Conclusions: The results of this case-control study demonstrate a higher frequency of dentine caries in patients with IBD but the periodontal findings showed no distinct differences between cases and controls.