Renal imaging at 7 Tesla: preliminary results
Renal imaging at 7 Tesla: preliminary results
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DOI：
10.1007/s00330-010-1962-9
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发表时间：
2011-04-01
影响因子：
5.9
通讯作者：
Lauenstein, Thomas C.
中科院分区：
文献类型：
--
作者：
Umutlu, Lale;Orzada, Stephan;Lauenstein, Thomas C.
为了研究利用定制的 8 通道发射/接收射频身体线圈对肾脏进行 7T MR 成像的可行性。在 7T 全身 MR 系统上对 8 名健康志愿者进行了体内非增强 MR。 B-0 匀场后，获得以下序列：1）2D 和 3D 损坏的梯度回波序列（FLASH、VIBE），2）T1 加权 2D 同相和反相 3）True-FISP 成像和 4）T2 加权涡轮自旋回波（TSE）序列。整体图像质量的视觉评估由两名放射科医生进行。7T 的肾脏 MRI 对所有八名受试者都是可行的。使用 T1 加权梯度回波 MRI 发现了最佳图像质量，提供了高解剖细节和非增强脉管系统的出色清晰度。通过成功的匀场，可以有效地减少 B-1 信号空白和/或将大多数序列类型移出感兴趣的区域。然而，由于三名志愿者的信号异质性，T2 加权 TSE 成像仍然具有挑战性并受到严重损害。结果证明了专用 7T 肾脏成像的可行性和诊断潜力。成像序列和专用射频线圈概念的进一步优化有望提高采集质量并最终提供较高的临床诊断价值。
To investigate the feasibility of 7T MR imaging of the kidneys utilising a custom-built 8-channel transmit/receive radiofrequency body coil.In vivo unenhanced MR was performed in 8 healthy volunteers on a 7T whole-body MR system. After B-0 shimming the following sequences were obtained: 1) 2D and 3D spoiled gradient-echo sequences (FLASH, VIBE), 2) T1-weighted 2D in and opposed phase 3) True-FISP imaging and 4) a T2-weighted turbo spin echo (TSE) sequence. Visual evaluation of the overall image quality was performed by two radiologists.Renal MRI at 7T was feasible in all eight subjects. Best image quality was found using T1-weighted gradient echo MRI, providing high anatomical details and excellent conspicuity of the non-enhanced vasculature. With successful shimming, B-1 signal voids could be effectively reduced and/or shifted out of the region of interest in most sequence types. However, T2-weighted TSE imaging remained challenging and strongly impaired because of signal heterogeneities in three volunteers.The results demonstrate the feasibility and diagnostic potential of dedicated 7T renal imaging. Further optimisation of imaging sequences and dedicated RF coil concepts are expected to improve the acquisition quality and ultimately provide high clinical diagnostic value.