The type of cement and failure of total hip replacements
The type of cement and failure of total hip replacements
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DOI：
10.1302/0301-620x.84b6.12776
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发表时间：
2002-08-01
影响因子：
--
通讯作者：
Vollset, SE
中科院分区：
文献类型：
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作者：
Espehaug, B;Furnes, O;Vollset, SE
使用挪威关节成形术登记处的数据，我们根据用于固定植入物的骨水泥类型评估了17,323个初级Charnley髋关节假体在骨关节炎患者中的存活率。总体而言，9.2%的患者在随访10年后进行了矫正；71%的失败涉及股骨假体的无菌性松动。我们观察到植入CMW1和CMW3骨水泥的假体失败率显著增加。以含庆大霉素的Palacos骨水泥固定的种植体为对照，调整后的Cox回归失败率分别为：纯Palacos粘固组1.1(95%CI 0.9~1.4)，单纯形组1.1(95%CI 0.7~1.6)，含庆大霉素的CMW1组2.1(95%CI 1.5~2.9)，普通CMW1组2.0(95%CI 1.6~2.4)，CMW3粘固剂固定组3.0(95%CI 2.3~3.9)。调整后的失败率在10年内从含有庆大霉素的Palacos固定的5.9%到CMW3固定的17%不等。
Using data from the Norwegian Arthroplasty Register, we have assessed the survival of 17 323 primary Charnley hip prostheses in patients with osteoarthritis based upon the type of cement used for the fixation of the implant. Overall, 9.2% had been revised after follow-up for ten years; 71% of the failures involved aseptic loosening of the femoral component. We observed significantly increased rates of failure for prostheses inserted with CMW1 and CMW3 cements. Using implants fixed with gentamicin-containing Palacos cement as the reference, the adjusted Cox regression failure rate ratios were 1.1 (95% CI 0.9 to 1.4) for implants cemented with plain Palacos, 1.1 (95% CI 0.7 to 1.6) for Simplex, 2.1 (95% 1.5 to 2.9) for gentamicin-containing CMW1, 2.0 (95% CI 1.6 to 2.4) for plain CMW1 and 3.0 (95% CI 2.3 to 3.9) for implants fixed with CMW3 cement. The adjusted failure rate at ten years varied from 5.9% for implants fixed with gentamicin-containing Palacos to 17% for those fixed with CMW3.