Preserved cardiac function after chronic spinal cord injury
Preserved cardiac function after chronic spinal cord injury
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DOI：
10.1016/j.apmr.2006.05.023
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发表时间：
2006-09-01
影响因子：
4.3
通讯作者：
Hopman, Maria T.
中科院分区：
文献类型：
--
作者：
de Groot, Patricia C.;van Dijk, Arie;Hopman, Maria T.
目标：评估慢性去适应对高度脊髓损伤（SCI）受试者心脏尺寸和功能的影响，SCI受试者代表人体体内极度不活动模型。设计：横断面研究。设置：大学医学中心。参与者：7名四肢瘫痪男性和7名健全对照。干预：不适用。主要结果测量：超声心动图测量静息心脏尺寸、收缩功能以及整体和长轴舒张功能。SCI患者的左心室质量指数显著低于对照组（90.8 +/-26 g/m2 vs 122 +/- 28.9g/m2; P= 0.05）。此外，与对照组相比，SCI患者的左心室、左心房和下腔静脉均显著缩小（P
Objective: To assess the effect of chronic deconditioning on cardiac dimensions and function in subjects with high-level spinal cord injury (SCI), who represent a human in-vivo model of extreme inactivity.Design: Cross-sectional study.Setting: University medical center.Participants: Seven men with tetraplegia and 7 able-bodied controls.Interventions: Not applicable.Main Outcome Measures: Echocardiographic measurements of resting cardiac dimensions, systolic function, and global and long-axis diastolic function.Results: Left ventricular mass index was significantly lower in the subjects with SCI than in the controls (90.8 +/- 26g/m(2) vs 122 +/- 28.9g/m(2); P=.05). In addition, dimensions of left ventricle, left atrium, and vena cava inferior were all significantly reduced in the subjects with SCI compared with 'controls (P