General Strategy To Make an On-Demand Library of Structurally and Functionally Diverse SERS Substrates
General Strategy To Make an On-Demand Library of Structurally and Functionally Diverse SERS Substrates
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DOI：
10.1021/acsanm.7b00385
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发表时间：
2018-02-01
影响因子：
5.9
通讯作者：
Dwyer, Jason R.
中科院分区：
文献类型：
--
作者：
Karawdeniya, Buddini Iroshika;Bandara, Y. M. Nuwan D. Y.;Dwyer, Jason R.
表面增强拉曼光谱(SERS)是一种有效的检测金属铸币表面附近分子的技术。SERS活性金属层及其支撑物的物理结构是一个关键的设计参数，它激励着基板制造中相当大的、而且往往是专门的努力。所需的金膜结构可以来自金属化过程和底层支撑结构，并且载体的结构可以提供包括诸如物理过滤等分析能力的附加功能。我们使用化学镀作为一种通用的方法来创建SERS基质库：在由各种材料制成的一系列支撑物上生成具有SERS活性的金膜，由简单和复杂的制造历史混合制成，并提供一系列结构衍生功能。结果是，由于增加了SERS传感，现有功能的支持能力得到了增强。因此，化学镀为纳米软化多功能SERS衬底提供了许多有益的特征，包括：对衬底成分和形状因数的容忍度；低设备开销要求；工艺化学灵活性-包括与传统的自上而下纳米制造的兼容性；作为一种简单的金属化技术，有着悠久的商业应用历史。我们的镀金标准纳米制造兼容的氮化硅支持表面具有平面和多孔结构，以及天然和聚合物接枝的表面化学。我们使用相同的电镀化学方法在商业滤纸中排列的纤维素纤维上形成具有SERS活性的金膜，并形成纳米纤维素纸。在功能意义上，我们使用化学镀来增强纳米孔过滤器、层析平台和具有SERS能力的纳米制造构件。
Surface-enhanced Raman spectroscopy (SERS) is a powerful technique for sensing molecules proximal to suitable coinage metal surfaces. The physical structure of the SERS-active metal layer and its support is a key design parameter inspiring considerable, and frequently specialized, efforts in substrate fabrication. The necessary gold film structure can arise from both the metallization process and the underlying support structure, and the structure of the support can deliver additional functions including analytical capabilities such as physical filtering. We used electroless plating as a general approach to create a library of SERS substrates: SERS-active gold films on a range of supports made from a variety of materials, made with a mixture of simple and complex fabrication histories, and offering a selection of structurally derived functions. The result was that supports with existing functions had their capabilities enhanced by the addition of SERS sensing. Electroless plating thus offers a host of beneficial characteristics for nanofabricating multifunctional SERS substrates, including the following: tolerance to substrate composition and form factor; low equipment overhead requirements; process chemistry flexibility-including compatibility with conventional top-down nanofabrication; and a lengthy history of commercial application as a simple metallization technique. We gold-plated standard nanofabrication-compatible silicon nitride support surfaces with planar and porous architectures, and with native and polymer-grafted surface chemistries. We used the same plating chemistry to form SERS-active gold films on cellulose fibers arrayed in commercial filter paper and formed into nanocellulose paper. In a functional sense, we used electroless plating to augment nanoporous filters, chromatography platforms, and nanofabrication building blocks with SERS capability.