Gold(I)-catalyzed stereoselective olefin cyclopropanation
Gold(I)-catalyzed stereoselective olefin cyclopropanation
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DOI：
10.1021/ja0552500
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发表时间：
2005-12-28
影响因子：
15
通讯作者：
Toste, FD
中科院分区：
文献类型：
--
作者：
Johansson, MJ;Gorin, DJ;Toste, FD
报道了以丙炔酯为金(I)-碳前体的三苯基磷金(I)催化烯烃环丙烷化反应。该反应为使用DTBM-SEGPHOS金(I)配合物作为催化剂制备高顺式选择性乙烯基环丙烷的对映选择性（高达94% ee）提供了基础。
A triphenylphosphinegold(I)-catalyzed cyclopropanation of olefins using propargyl esters as gold(I)−carbene precursors is reported. This reaction provided the basis for the use of a DTBM-SEGPHOS gold(I) complex as a catalyst in the enantioselective (up to 94% ee) preparation of vinyl cyclopropanes with highcis-selectivity.