EFFECT OF ARTIFICIAL PANCREAS TREATMENT ON PERIPHERAL-NERVE FUNCTION IN DIABETES
EFFECT OF ARTIFICIAL PANCREAS TREATMENT ON PERIPHERAL-NERVE FUNCTION IN DIABETES
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DOI：
10.1212/wnl.31.11.1375
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发表时间：
1981-01-01
期刊：
影响因子：
9.9
通讯作者：
DYCK, PJ
中科院分区：
文献类型：
--
作者：
SERVICE, FJ;DAUBE, JR;DYCK, PJ
为了确定完全纠正糖尿病高血糖是否可以快速改善异常的周围神经功能，8 名需要胰岛素的高血糖糖尿病患者接受了为期 3 天的人工内分泌胰腺（Biostator 血糖控制器）的血糖控制。 Biostator 治疗前后的神经系统评估比较显示，仅尺神经感觉传导速度（+3.2 .+-. 1.4 m/s）有所改善，其他 24 项神经传导测量、计算机辅助感觉检查和神经系统评估评分没有显着变化。纠正高血糖对神经功能产生的任何显着有益影响可能需要 3 天以上才能显现出来。
To determine whether the complete correction of hyperglycemia of diabetes can rapidly improve abnormal peripheral nerve function, 8 hyperglycemic insulin-requiring diabetics underwent 3 days of glucose control with an artificial endocrine pancreas, the Biostator Glucose Controller. Comparison of neurologic assessment before and after Biostator treatment showed improvement only in ulnar sensory conduction velocity (+3.2 .+-. 1.4 m/s) and no significant changes in 24 other nerve conduction measurements, computer-assisted sensory examination and scored neurologic assessment. Any significant beneficial effect on nerve function resulting from correction of hyperglycemia probably requires more than 3 days to be manifested.