Nickel-catalyzed C-O bond reduction of aryl and benzyl 2-pyridyl ethers
Nickel-catalyzed C-O bond reduction of aryl and benzyl 2-pyridyl ethers
复制标题
镍催化芳基和苄基 2-吡啶基醚的 C-O 键还原
DOI：
10.1039/c7cc09668b
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发表时间：
2018-02-28
影响因子：
4.9
通讯作者：
Wang, Zhong-Xia
中科院分区：
文献类型：
--
作者：
Li, Jing;Wang, Zhong-Xia
异丙醇钠通过镍催化的C-OPy键断裂还原芳基和苄基2-吡啶醚，以合理的产率得到还原产物。该方法具有反应效率高、反应条件温和、官能团配伍性好等优点，可直接脱除2-吡啶氧基。
The reduction of aryl and benzyl 2-pyridyl ethers with sodium isopropoxide was carried out via nickel-catalyzed C-OPy bond cleavage, giving reductive products in reasonable to excellent yields. This method allowed the 2-pyridyloxy group to be directly removed with high efficiency, mild reaction conditions, and good compatibility of functional groups.