Recent advances of transient isotachophoresis‐capillary electrophoresis in the analysis of small ions from high‐conductivity matrices
Recent advances of transient isotachophoresis‐capillary electrophoresis in the analysis of small ions from high‐conductivity matrices
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DOI：
10.1002/elps.200500320
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发表时间：
2006
期刊：
影响因子：
2.9
通讯作者：
A. Timerbaev;T. Hirokawa
中科院分区：
文献类型：
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作者：
A. Timerbaev;T. Hirokawa
自从CE进入小离子分析领域以来，痕量离子分析物的定量一直是一项具有挑战性的任务，特别是在处理高盐样品时。本文综述了该方法与瞬态ITP （tITP）在线富集相结合的进展和重大进展。考虑了高电导率溶液中tITP的堆叠原理和操作预富集模式。本综述涵盖的最重要的应用领域包括海水和生物流体（尿液、血清等）的分析。本文引用的例子表明，当以测定负载基质中的痕量离子为目的时，tITP‐CE正在成为一种公认的技术。
Since its invasion into the field of small ion analysis, quantitation of trace ionic analytes has always been a challenging task for CE, especially when dealing with highly saline samples. This review summarizes the method's progress and significant developments in the area due to its combination with on‐line preconcentration by transient ITP (tITP). Principles of tITP stacking in high‐conductivity solutions and operational preconcentration modes are considered. The most important application areas covered in this review include the analysis of seawater and biological fluids (urine, serum, etc.). Examples cited in this review demonstrate that tITP‐CE is now on a certain way of becoming a recognized technique when the determination of trace ionic species in loaded matrices is the aim.