Insights into the functional specificity of the human corpus callosum

Insights into the functional specificity of the human corpus callosum
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DOI:
10.1093/brain/123.5.920
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发表时间:
2000-05-01
期刊:
影响因子:
14.5
通讯作者:
Gazzaniga, MS
Gazzaniga, MS
中科院分区:
医学1区
文献类型:
--
作者:
Funnell, MG;Corballis, PM;Gazzaniga, MS

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患者VP在27岁时为控制顽固性癫痫接受了完全的膝盖骨切开术。然而,在随后的MRI中,我们报告了一系列实验,以确定这些纤维是否支持两个大脑半球之间的信息功能传递。虽然我们没有发现颜色、形状或大小信息转移的证据,但有很好的证据证明文字信息转移。这些结果表明,Vp内备用的脾纤维是物质特异性的,说明了其功能特异性的显著程度。
Patient VP underwent complete callosotomy for the control of intractable epilepsy at the age of 27 years. Subsequent MRI, however, revealed spared callosal fibres in the rostral and splenial ends of the corpus callosum, We report a series of experiments designed to determine whether these fibres support functional transfer of information between the two cerebral hemispheres. Although we found no evidence for transfer of colour, shape or size information, there is good evidence for transfer of word information. This suggests that the spared splenial fibres in VP's corpus callosum are material-specific, The results of these experiments illustrate the remarkable degree of functional specificity within the corpus callosum.