Potential Use of Environmental Biological Samples for Retrospective Electron Paramagnetic Resonance Dosimetry of Radiation Accidents
Potential Use of Environmental Biological Samples for Retrospective Electron Paramagnetic Resonance Dosimetry of Radiation Accidents
复制标题
环境生物样本用于辐射事故回顾性电子顺磁共振剂量测定的潜在用途
DOI：
10.3390/app10196867
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发表时间：
2020
期刊：
影响因子：
--
通讯作者：
L. Lai
中科院分区：
文献类型：
--
作者：
Chia;Hsin;Ching;Fu;Jao;L. Lai
回顾性剂量测定是发生大规模放射性事件和核大规模伤亡事件时环境剂量估算的最重要的事故剂量测定工具之一。电子顺磁共振（EPR）剂量测定是一种基于材料中稳定辐射诱导自由基的测量来回顾性评估吸收剂量的物理方法。与水体系中自由基的快速消失不同，自由基可以在某些有组织的基质中无限期地存在。因此，海洋或陆地生物中所含的环境材料可以用作环境剂量计，进行回顾性剂量分析。本研究旨在评估环境生物样本中自由基的 EPR 信号，可能用于回顾性剂量估计。评估的样品包括牛骨、青蛤壳、蛤壳、鱿鱼的甲壳素和人体组织（牙釉质和指甲）。首先，我们将这些材料脱水并研磨成不同尺寸的粉末。随后，使用6 MV直线加速器对所有材料进行5 Gy至50 Gy不同剂量的辐照，并通过峰峰值幅度的计算获得这些材料的EPR谱。六种材料的EPR信号与辐照剂量的剂量反应曲线显示出良好的线性（R2~0.99）。对于粒度实验，0.5毫米的牛骨和牙齿、0.1毫米的甲壳素和1毫米的其他信号最强。对于存储温度实验，牙齿、指甲、牛骨和甲壳素的最佳存储温度为-20°C，蛤壳和青蛤壳的最佳存储温度为45°C，此时信号衰减最小。总之，所建立的六种材料的剂量响应曲线可能有助于在辐射事故发生时的环境下进行快速、粗略的回顾性剂量重建。
Retrospective dosimetry is one of the most important tools of accident dosimetry for environmental dose estimation when large-scale radiological incidents and nuclear mass-casualty events occur. Electron paramagnetic resonance (EPR) dosimetry is a physical method for the retrospective assessment of absorbed dose based on the measurement of stable radiation-induced radicals in materials. Different from the fast disappearance of radials in aqueous systems, the radials can persist indefinitely in some organized matrices. Therefore, environmental materials contained in creatures from sea or land can be potentially used as environmental dosimeters for a retrospective dose analysis. This study aims to assess the EPR signals of free radicals from environmental biological samples, potentially for the retrospective dose estimation. The evaluated samples involve ox bone, cyclina shell, clam shell, chitin from squid, and human tissue (enamel and fingernail). First, we dehydrate and grind these materials to the powder with different sizes. Subsequently, all materials were irradiated with different doses ranging from 5 Gy to 50 Gy using 6 MV linear accelerator, and EPR spectra of these materials were obtained from the calculation of peak-to-peak amplitudes. The dose-response curve of EPR signals versus irradiated dose for the six materials shows good linearity (R2~0.99). For the grain-size experiment, the ox bone and tooth with 0.5 mm, the chitin with 0.1 mm, and the others with 1 mm have the strongest signal. For the storage temperature experiment, the optimal temperature of storage is at −20 °C for tooth, fingernail, ox bone, and chitin, at 45 °C for clam shell and cyclina shell where the signal fading is minimal. In conclusion, the developed dose-response curves of the six materials may potentially help a fast, rough retrospective dose reconstruction under the environment when radiation accidents occur.
影响因子：
2
作者：
Trompier, F.;Kornak, L.;Clairand, I.
通讯作者：
Clairand, I.
DOI：
10.1016/j.radphyschem.2017.06.009
发表时间：
2017-12
期刊：
Radiation physics and chemistry (Oxford, England : 1993)
影响因子：
--
作者：
Sholom S;McKeever S
通讯作者：
McKeever S