Effects of estrogen therapy on hearing in postmenopausal women
Effects of estrogen therapy on hearing in postmenopausal women
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DOI：
10.1016/j.ajog.2003.06.001
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发表时间：
2004-01-01
影响因子：
9.8
通讯作者：
Kazanci, F
中科院分区：
文献类型：
--
作者：
Kilicdag, EB;Yavuz, H;Kazanci, F
目的：本研究旨在探讨激素治疗对绝经后妇女听力的影响。研究设计：本前瞻性研究包括109名绝经后妇女。其中20名妇女使用雌激素治疗（ET组），30名妇女使用激素治疗（HT组），59名妇女没有接受任何形式的激素治疗（对照组）。耳镜检查显示所有109名受试者的鼓膜均正常。每个人都进行了测试，低-（250-2000赫兹）和高频测听（4000-16000赫兹）。激素治疗的持续时间进行了记录，患者的特点（年龄，绝经类型，绝经后的时间），体重指数（BMI），和听力测试结果在ET，HT，和control groups.Results：有没有统计学差异治疗（ET和HT组）和对照组之间的年龄，BMI，或绝经后的时间。HT和ET的平均时间分别为4.13+/-2.41年和3.35+/-2.20年。ET组在低频（250、500、1000和2000 Hz）的平均气导结果显著高于对照组（P
Objective: This study was undertaken to investigate how hormone therapy affects hearing in postmenopausal women.Study design: This prospective study involved 109 postmenopausal women. Twenty of the women were using estrogen therapy (ET group), 30 women were using hormone therapy (HT group), and 59 had not received hormone therapy of any kind (control group). Otoscopic examination revealed normal tympanic membranes in all 109 subjects. Each individual was tested with low- (250-2000 Hz) and high-frequency audiometry (4000-16000 Hz). Duration of hormone therapy was recorded, and patient characteristics (age, type of menopause, time since onset of menopause), body mass index (BMI), and hearing test results in the ET, HT, and control groups were compared.Results: There were no statistically significant differences between the treatment (ET and HT group) and control groups with respect to age, BMI, or time since onset of menopause. The mean time on HT and ET was 4.13+/-2.41 years and 3.35+/-2.20 years, respectively. The mean air conduction results at low frequencies (250, 500, 1000, and 2000 Hz) in the ET group were significantly higher than the corresponding findings in the control group (P