Elevated free triiodothyronine may lead to female sexual dysfunction in Chinese urban women: A hospital-based survey.
Elevated free triiodothyronine may lead to female sexual dysfunction in Chinese urban women: A hospital-based survey.
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DOI：
10.1038/s41598-017-01352-9
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发表时间：
2017-04-27
影响因子：
4.6
通讯作者：
Zhu J
中科院分区：
文献类型：
--
作者：
Luo H;Yang H;Zhao W;Han Q;Zeng L;Tang H;Zhu J
由于保守的文化和信仰，对女性性功能障碍（FSD）的研究有限，尤其是在中国。自2014年中国版女性性功能指数（CVFSFI）最佳临界值确定以来，国内FSD筛查研究一直较为匮乏。同时，中国女性中甲状腺激素与FSD之间的关系也很少被探索。因此，进行了以医院为基础的研究，以阐明 FSD 频率和危险因素。我们邀请在健康促进中心接受检查的女性参加，如果同意，则被纳入研究。提取了人口统计和社会经济数据。所有参与者均完成了 CVFSFI 和贝克抑郁量表 (BDI) 自我报告问卷，并接受了甲状腺激素测试。最终分析共有1119名参与者，平均年龄38.6±7.6岁，平均CVFSFI评分为25.7±3.9。在这项以医院为基础的横断面研究中，参与者中 FSD 的发生率为 26.5%。除年龄、绝经、产次和抑郁状况作为危险因素，年收入（4万-10万元/年）和教育背景（≥大学）作为保护因素外，游离三碘甲状腺原氨酸（fT3）升高被确定为FSD的独立危险因素。
Research on female sexual dysfunction (FSD) is limited, especially in China, due to conservative culture and beliefs. There has been a dearth of FSD screening research in China since the optimal cutoff value of the Chinese version of the Female Sexual Function Index (CVFSFI) was determined in 2014. At the same time, the relationship between thyroid hormones and FSD has seldom been explored in Chinese women. Therefore, hospital-based research was conducted to elucidate FSD frequency and risk factors. Women who underwent a check-up at the Health Promotion Center were approached to participate and, if consented, were enrolled in the study. Demographic and socioeconomic data was extracted. All participants completed the CVFSFI and Beck Depression Inventory (BDI) self-report questionnaires and underwent thyroid hormone tests. A total of 1119 participants were included in the final analysis, with a mean age of 38.6 ± 7.6 years and average CVFSFI score of 25.7 ± 3.9. The frequency of FSD among the participants in this hospital-based cross-sectional study was 26.5%. In addition to age, menopause, parity and depression status as risk factor, and annual income (40,000–100,000 RMB/year) and educational background (≥university) as protective factor, elevated free triiodothyronine (fT3) was identified as an independent risk factor of FSD.