Prevalence of dementia and dementing diseases in the old-old population in Japan: the Kurihara Project. Implications for Long-Term Care Insurance data
Prevalence of dementia and dementing diseases in the old-old population in Japan: the Kurihara Project. Implications for Long-Term Care Insurance data
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DOI：
10.1111/j.1479-8301.2012.00406.x
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发表时间：
2012-12-01
期刊：
影响因子：
2
通讯作者：
Ouchi, Yoshitaka
中科院分区：
文献类型：
--
作者：
Meguro, Kenichi;Tanaka, Naofumi;Ouchi, Yoshitaka
背景：目前还没有关于日本老年人痴呆患病率的报道。方法：我们研究了日本北部栗原市的老年人口。对参与者 1 (n = 590) 进行分析 1，通过包括 MRI 在内的强化评估来评估痴呆和痴呆疾病的患病率。分析 2 旨在根据长期护理保险指数确定一个检测疑似痴呆症的良好指标。参与者 2 (n = 3915) 的分析 3 旨在估计疑似痴呆症的患病率。结果：在分析 1 中，73 人 (12.4%) 被诊断患有痴呆症。最常见的原因是阿尔茨海默病合并脑血管疾病。在分析 2 中，发现痴呆症受损水平 I 级是疑似痴呆症状况的良好指标。在分析 3 中，疑似痴呆症的总体估计患病率为 23.6%。男性中，这一比例从75岁至87岁逐渐上升至20%左右，88岁时上升至40%，此后趋于稳定。相比之下，在女性中，这一比例从75岁上升到95岁以上，达到70%左右。结论：患病率高于之前报道的患病率。性别之间存在差异：男性出现与年龄相关的增加，而女性则出现与年龄相关的增加。阿尔茨海默氏病伴脑血管疾病是最常见的原因，这与之前针对 65 岁及以上人群的发现相吻合；然而，混合性痴呆的比例更大。
Background: There have been no reports on the prevalence of dementia among the old-old people in Japan. Methods: We studied the old-old population in Kurihara, northern Japan. Analysis 1 of Participants 1 (n = 590) was performed to evaluate the prevalence of dementia and dementing diseases by intensive evaluation including MRI. Analysis 2 aimed to determine a good indicator for detecting suspected dementia condition based on the Long-Term Care Insurance index. Analysis 3 of Participants 2 (n = 3915) aimed to estimate the prevalence of suspected dementia condition. Results: In Analysis 1, 73 people (12.4%) were diagnosed with dementia. The most common cause was Alzheimer's disease with cerebrovascular disease. In Analysis 2, level I of the Impairment Level of Dementia was found to be a good indicator of suspected dementia condition. In Analysis 3, the overall estimated prevalence of suspected dementia condition was 23.6%. In men, the ratio increased gradually from 75 to 87 years old to about 20%, increased to 40% at the age of 88 and became stable thereafter. In contrast, in women, the ratio increased from 75 to 95+ years old, reaching about 70%. Conclusions: The prevalence was higher than that reported previously. There was a difference between the sexes: an age-related increase occurred in men and an ageing-related increase in women. Alzheimer's disease with cerebrovascular disease was the most common cause, which coincided with the previous findings of individuals aged 65 years and older; however, the ratio of mixed dementia was greater.