The utility of diffusion-weighted imaging to assess acute renal parenchymal changes due to unilateral ureteral stone obstruction
The utility of diffusion-weighted imaging to assess acute renal parenchymal changes due to unilateral ureteral stone obstruction
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DOI：
10.1007/s00240-016-0924-3
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发表时间：
2017-08-01
期刊：
影响因子：
3.1
通讯作者：
Erdem, Gulnur
中科院分区：
文献类型：
--
作者：
Duzenli, Kursat;Ozturk, Mehmet;Erdem, Gulnur
本研究的目的是评价弥散加权成像（DWI）在单侧输尿管结石梗阻所致急性肾实质改变中的应用。本前瞻性研究纳入了24例梗阻和对侧通畅肾患者。在两个不同的B值（B = 0 s/mm（2）和B = 1000 s/mm（2））下使用DWI。测量双肾上极、中段和下极实质的表观扩散系数（ADC）。计算ADC值。使用非配对t检验评估组间差异。测量结果表明，与未阻塞的对侧肾实质相比，阻塞肾实质的ADC值降低。上下极实质ADC值的降低更大，具有统计学显著性（p < 0.001）。DWI可定量显示急性单侧输尿管结石梗阻时肾实质的弥散改变。ADC值的降低在上极和下极实质中更明显。
Our aim in this study was to evaluate the use of diffusion-weighted imaging (DWI) for acute renal parenchymal changes occurring as a result of unilateral ureteral obstruction due to stones. Twenty four patients with obstructed and opposite unobstructed kidney were enrolled in this prospective study. DWI was used at two different b values (b = 0 s/mm(2) and b = 1000 s/mm(2)). Apparent diffusion coefficient (ADC) measurements were completed on the upper pole, central section and lower pole parenchyma of both kidneys. ADC values were calculated. The unpaired t test was used to assess differences between the groups. The results of measurements identified a reduction in ADC values in obstructed renal parenchyma compared to unobstructed opposite renal parenchyma. The reduction in ADC values was greater in the upper and lower pole parenchyma and was statistically significant (p < 0.001, for both). Diffusion changes in renal parenchyma due to acute unilateral ureteral obstruction linked to stone may be quantitatively shown with DWI. The reduction in ADC values was more pronounced in the upper and lower pole parenchyma.