Three-dimensional systolic strain patterns in the normal human left ventricle: Characterization with tagged MR imaging
Three-dimensional systolic strain patterns in the normal human left ventricle: Characterization with tagged MR imaging
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DOI：
10.1148/radiology.214.2.r00fe17453
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发表时间：
2000-02-01
期刊：
影响因子：
19.7
通讯作者：
Zerhouni, EA
中科院分区：
文献类型：
--
作者：
Moore, CC;Lugo-Olivieri, CH;Zerhouni, EA
目的：建立人体正常左心室(LV)收缩期三维应变演化数据库。材料与方法：对31名健康志愿者采用磁共振组织标记法和屏气磁共振成像法，每隔32ms产生并检测心脏内瞬时基准标记物(TAG)的运动。根据与标签数据相匹配的3D位移场计算应变和运动。基于多个应变分量的收缩和增厚的特殊指标也被评估。结果：局部应变在收缩前半期呈线性时间演变。峰值缩短和增厚的应变分量通常在前外侧壁最大，向心尖部增加，向心内膜增加。剪切力和位移在空间上的变化更大。与传统的应变分量相比，收缩和增厚这两个专门指标具有更高的测量精度和更窄的正常范围。结论：本研究无创性地表征了人体左室壁三维位移和应变演化的正常收缩范围。与这个多维数据库的比较可能使收缩功能不全的敏感检测成为可能。
PURPOSE: To present a database of systolic three-dimensional (3D) strain evolution throughout the normal left ventricle (LV) in humans.MATERIALS AND METHODS: In 31 healthy volunteers, magnetic resonance (MR) tissue tagging and breath-hold MR imaging were used to generate and then detect the motion of transient fiducial markers (ie, tags) in the heart every 32 msec. Strain and motion were calculated from a 3D displacement field that was fit to the tag data. Special indexes of contraction and thickening that were based on multiple strain components also were evaluated.RESULTS: The temporal evolution of local strains was linear during the first half of systole. The peak shortening and thickening strain components were typically greatest in the anterolateral wall, increased toward the apex, and increased toward the endocardium. Shears and displacements were more spatially variable. The two specialized indexes of contraction and thickening had higher measurement precision and tighter normal ranges than did the traditional strain components.CONCLUSION: In this study, the authors noninvasively characterized the normal systolic ranges of 3D displacement and strain evolution throughout the human LV. Comparison against this multidimensional database may permit sensitive detection of systolic LV dysfunction.