Severe respiratory disease in dairy cows caused by infection with bovine respiratory syncytial virus
Severe respiratory disease in dairy cows caused by infection with bovine respiratory syncytial virus
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DOI：
10.1136/vr.138.5.101
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发表时间：
1996-02-03
影响因子：
2.2
通讯作者：
Elvander, M
中科院分区：
文献类型：
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作者：
Elvander, M
1988年及之后，瑞典各地的奶牛群中都记录到了由牛呼吸道合胞体病毒（BRSV）引起的严重呼吸道疾病的暴发。通过培养、聚合酶链反应（PCR）以及免疫荧光法，在处于疾病急性期的动物的鼻咽拭子样本中检测到了该病毒。来自所调查牛群的血清学数据显示，奶牛是对BRSV而非牛冠状病毒、牛病毒性腹泻病毒或副流感3型病毒发生了血清转化。主要是偏远地区的奶牛群感染了严重的原发性BRSV，通常是在购入新动物之后。一项针对混合牛奶样本中BRSV抗体的全国性调查显示，瑞典最南部地区的患病率最高，为84% - 89%，而该国北部的患病率最低，为41% - 51%。BRSV的患病率在牛数量最多的地区最高。
Outbreaks of severe respiratory disease caused by bovine respiratory syncytial virus (BRSV) were recorded in dairy herds throughout Sweden in 1988 and subsequently. The virus was demonstrated in nasopharyngeal swab material from animals in the acute stage of the disease by culture, the polymerase chain reaction (PCR) and by immunofluorescence. Serological data from the herds investigated showed that the cows had seroconverted to BRSV rather than to bovine coronavirus, bovine viral diarrhoea virus or parainfluenza-3 virus. It was predominantly dairy herds in isolated areas that contracted a severe primary BRSV infection, often after the purchase of new animals. A nationwide survey for BRSV antibodies in bulk milk samples showed the highest prevalence, of 84 to 89 per cent, in the southernmost regions of Sweden and the lowest prevalence, of 41 to 51 per cent, in the north of the country. The prevalence of BRSV was highest in areas with the highest populations of cattle.