Pre-pregnant body mass index, weight gain and the risk of delivering large babies among non-diabetic mothers
Pre-pregnant body mass index, weight gain and the risk of delivering large babies among non-diabetic mothers
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DOI：
10.1016/j.ijgo.2007.02.001
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发表时间：
2007-05-01
影响因子：
3.8
通讯作者：
Werler, M. M.
中科院分区：
文献类型：
--
作者：
Kabali, C.;Werler, M. M.
目的：怀孕前超重和怀孕期间体重过度增加都与分娩大婴儿的风险增加有关。然而，以前的研究集中在糖尿病女性这两个体重指数的单独影响。方法：本研究分析了815名非糖尿病妇女的孕前体重指数和体重增加与巨大儿（>= 4000 g）的单独和联合影响，使用的数据收集自一项回顾性研究。测试结果：与孕前体重指数正常且孕期体重增加的母亲相比，只有体重增加过多的超重妇女的后代发生巨大儿的风险显著升高（校正OR=2.6，95% CI [1.2，5.4]），但在体重正常且增重过多的母亲中并非如此（校正OR=1.1，95% CI [0.5，2.4]）或体重正常或低增重的超重母亲（校正OR=1.1，95% CI [0.4，3.1]）。结论：考虑到与分娩大婴儿有关的并发症，超重妇女可能会从怀孕期间不增加体重中受益。(C)2007年国际妇产科联合会。由Elsevier爱尔兰有限公司出版。保留所有权利。
Objective: Pre-pregnancy overweight and excess weight gain during pregnancy have each been associated with an increased risk of delivering large babies. However, previous studies have focused on the separate effects of these two indices of weight in diabetic women. Method: This study analyzed both separate and combined effects of pre-pregnant body mass index and weight gain in relation to macrosomia (>= 4000 g) in offspring among 815 non-diabetic women, using data collected from a retrospective study. Result: Compared to mothers with normal pre-pregnancy BMI and pregnancy weight gain, risk of macrosomia in offspring was significantly elevated only in overweight women with excess weight gain (adjusted OR=2.6, 95% Cl [1.2,5.4]) but not among normal weight mothers with excess gain (adjusted OR=1.1, 95% Cl [0.5,2.4]) or overweight mothers with normal or tow gain (adjusted OR=1.1, 95% Cl [0.4,3.1]). Conclusion: Given the complications that are associated with delivering large babies, overweight women may benefit from not gaining excess weight in pregnancy. (C) 2007 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.