ESOPHAGEAL INVOLVEMENT IN BEHCETS-DISEASE - IS ENDOSCOPY NECESSARY

ESOPHAGEAL INVOLVEMENT IN BEHCETS-DISEASE - IS ENDOSCOPY NECESSARY
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DOI:
10.1007/bf01307585
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发表时间:
1992-04-01
影响因子:
3.1
通讯作者:
BENNETT, JR
BENNETT, JR
中科院分区:
医学3区
文献类型:
--
作者:
BOTTOMLEY, WW;DAKKAK, M;BENNETT, JR

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1976年至1990年间被诊断为白塞病的20名患者被要求到皮肤科就诊,以便根据最近建立的白塞病诊断标准来审查他们的诊断。10名患者符合诊断标准,其中9名患者同意参与这项内窥镜研究。9例患者接受了上消化道内窥镜检查,其中3例单纯消化不良,2例有吞咽困难和消化不良,1例有反酸症状,其余患者在内窥镜检查时没有症状。1例有1级反流性食管炎的证据,1例偶发幽门管溃疡,1例出现严重吞咽困难,发现有高位食道狭窄并伴有溃疡。白塞氏病很少影响食道,但一旦出现,可引起明显的食管炎,继而形成狭窄。由于食道受累的发生率很低(11%),我们得出结论,除非患者有明显的食道症状,否则没有白塞病患者常规内窥镜检查的指征。
Twenty patients who were diagnosed as having Behcet's Disease between 1976 and 1990 were asked to attend the dermatology department so that their diagnosis could be reviewed in the light of recently established criteria for the diagnosis of Behcet's disease. Ten patients fulfilled the diagnostic criteria, nine of whom agreed to participate in this endoscopic study. Nine patients underwent upper gastrointestinal endoscopy, three of whom had dyspepsia alone, two had dysphagia and dyspepsia, one had symptoms of acid regurgitation, and the remainder were asymptomatic at the time of endoscopy. One patient had evidence of grade 1 reflux esophagitis, one had an incidental pyloric canal ulcer, and one patient who had severe dysphagia on presentation was found to have a high esophageal stricture with accompanying ulceration. Behcet's disease rarely affects the esophagus but when present can cause marked esophagitis with consequent stricture formation. Since the incidence of esophageal involvement was low (11%), we conclude that unless the patient had marked esophageal symptoms there is no indication for routine endoscopy of patients with Behcet's disease.