Predictors of functional and exercise amenorrhoea among eating and exercise disordered patients
Predictors of functional and exercise amenorrhoea among eating and exercise disordered patients
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DOI：
10.1093/humrep/dei294
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发表时间：
2006-01-01
影响因子：
6.1
通讯作者：
Russell, J
中科院分区：
文献类型：
--
作者：
Abraham, SF;Pettigrew, B;Russell, J
背景技术背景：本研究的目的是调查患有或正在从饮食或运动障碍中恢复的患者自我报告的闭经的预测因素。方法：对268例16-40岁未服用口服避孕药或激素替代的女性患者在入院时或12个月后的月经状况、饮食和运动行为和感觉以及体重史进行了评估。结果：继发性闭经134例，月经过少39例，自然月经规律95例。闭经发生在所有类型的饮食失调诊断的女性中，包括EDNOS（饮食失调未分类）。继发性闭经的预测因素是：较低的当前BMI [比值比（OR）0.59，置信区间（CI）0.50-0.68];体重减轻量较大（OR 1.19，CI 1.06-1.33）;出于情绪、燃烧能量或身体形象原因而锻炼（OR 1.50，CI 1.14-1.97）;和年轻化（OR 0.93，CI 0.87-1.00）。与没有运动障碍的进食障碍患者相比，患有运动障碍的进食障碍患者更有可能报告试图减少食物摄入量，感觉必须运动和患有闭经/月经过少。结论：与能量债务相关的自我报告行为和感觉越大，月经就越有可能受到干扰。需要对所有的闭经患者进行能量平衡评估。
BACKGROUND: The aim of this study was to investigate the predictors of amenorrhoea self-reported by patients who are suffering or recovering from eating or exercise disorders. METHODS: Menstrual status, eating and exercise behaviours and feelings, and weight history of 268 female patients, 16-40 years old and not taking oral contraception or hormone replacement, were assessed on admission to hospital or 12 months later. RESULTS: Most (134) had secondary amenorrhoea, 39 had oligomenorrhoea and 95 regular spontaneous menses. Amenorrhoea occurs in women with all types of eating disorder diagnoses including EDNOS (eating disorder not otherwise classified). The predictors of secondary amenorrhoea were: lower current BMI [odds ratio (OR) 0.59, confidence interval (CI) 0.50-0.68); a greater amount of body weight lost (OR 1.19, CI 1.06-1.33); exercising for mood, to burn up energy or for body image reasons (OR 1.50, CI 1.14-1.97); and younger age (OR 0.93, CI 0.87-1.00). Eating disorder patients with an exercise disorder were significantly more likely to report trying to reduce their food intake, to feel compelled to exercise and to have amenorrhoea/ oligomenorrhoea than eating disorder patients without an exercise disorder. CONCLUSION: The greater the self-report behaviours and feelings associated with energy debt, the more likely menstruation is to be disturbed. Energy balance needs to be assessed in all amenorrhoeic patients.