TERPENOIDS .11. INVESTIGATION OF NINE CACTUS SPECIES - ISOLATION OF 2 NEW TRITERPENES, STELLATOGENIN AND MACHAERIC ACID
TERPENOIDS .11. INVESTIGATION OF NINE CACTUS SPECIES - ISOLATION OF 2 NEW TRITERPENES, STELLATOGENIN AND MACHAERIC ACID
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DOI：
10.1021/ja01610a033
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发表时间：
1955-01-01
影响因子：
15
通讯作者：
TAYLOR, BJ
中科院分区：
文献类型：
--
作者：
DJERASSI, C;LIU, LH;TAYLOR, BJ
描述了对来自墨西哥、哥斯达黎加和秘鲁的九种仙人掌的化学检查。除了已知的三萜齐墩果酸（I）和桦木酸（III）之外，还遇到了两种新的三萜。从 L. stellatus 和 M. eruca 中分离出一种新的二羟基内酯，即 stellatogenin，通过与仙人掌三萜 thuberogenin 直接相关，显示其具有一个仲羟基和一个叔羟基官能团。记录了从 M.gummosus 中分离出第二种新的三萜，即 Machaeric 酸（21-酮基齐墩果酸）(II)。我们对某些巨型仙人掌中三萜糖苷的初步观察1·3 促使我们对该植物家族进行更广泛的研究。我们现在要报告九种仙人掌物种，就其自然栖息地而言，它们的分布范围从墨西哥北部到秘鲁。
The chemical examination of nine cacti from Mexico, Costa Rica and Peru is described. In addition to the known tri-terpenes oleanolic acid (I) and betulinic acid (III), two new triterpenes were encountered. From L. stellatus and M. eruca there was isolated a new dihydroxy lactone, stellatogenin, which was shown to possess one secondary and one tertiary hydroxyl function by direct correlation with the cactus triterpene thurberogenin. The isolation of a second new triterpene, machaeric acid (21-keto-oleanolic acid)(II), from M. gummosus is recorded.Our initial observation1· 3 of the occurrence of triterpene glycosides in certain giant cacti has prompted us to undertake a more extensive study of thisplant family. We should now like to report on nine cactus species which range, as far as their natural habitats are concerned, from Northern Mexico to Peru.