TOPOGRAPHY OF THE ESOPHAGEAL PERISTALTIC PRESSURE WAVE
TOPOGRAPHY OF THE ESOPHAGEAL PERISTALTIC PRESSURE WAVE
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DOI：
10.1152/ajpgi.1991.261.4.g677
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发表时间：
1991-10-01
影响因子：
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通讯作者：
STAIANO, A
中科院分区：
文献类型：
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作者：
CLOUSE, RE;STAIANO, A
为了更好地了解蠕动收缩的空间关系，对12名健康志愿者进行了常规食管测压波构造的地形图的检查。典型的减后波在空间上通过计算机网格和绘图系统相互连接。由此产生的蠕动收缩的轮廓图显示，在食管长度的21.7 +/- 1.3%处，近端压力段与明显的远端收缩一致分离。在64.0 +/- 2.7%的食管长度处，11例（91.7%）患者出现第二个收缩槽，将远端（平滑肌）食管分成两个收缩段。类似的地形研究也在8例频繁出现双峰波的有症状患者中进行。8例患者中有6例（75%）观察到两个远端收缩节段排列不良。这些地形图显示了以前未被识别的波关系，并表明在食管远端平滑肌中可以检测到两个神经肌肉收缩单元。这项技术对于理解这些单位在不同生理条件下或与疾病的关系变化是有用的。
Topographic plots constructed from conventional esophageal manometric waves were examined in 12 healthy volunteers to better understand spatial relationships of peristaltic contractions. Typical postdeglutitive waves were spatially interconnected using a computerized gridding and plotting system. Contour plots of the resultant peristaltic contraction revealed a consistent separation of a proximal pressure segment from the prominent distal contraction at 21.7 +/- 1.3% of the esophageal length. A second trough in the contraction sequence was found in 11 (91.7%) of the subjects at 64.0 +/- 2.7% of esophageal length separating the distal (smooth muscle) esophagus into two contraction segments. Similar topographic studies were also performed in eight symptomatic patients with frequent double-peaked waves. Poor alignment of the two distal contraction segments was observed in six (75%) of the eight patients. These topographic plots demonstrate previously unrecognized wave relationships and suggest that two neuromuscular contraction units can be detected in the distal smooth muscle esophagus. This technique should be useful in understanding altered relationships of these units under differing physiological conditions or with disease.