Transvenous pacing lead-induced thrombosis: A series of cases with a review of the literature
Transvenous pacing lead-induced thrombosis: A series of cases with a review of the literature
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DOI：
10.1159/000007018
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发表时间：
2000-01-01
期刊：
影响因子：
1.9
通讯作者：
Spurrell, RAJ
中科院分区：
文献类型：
--
作者：
Barakat, K;Robinson, NM;Spurrell, RAJ
尽管经静脉起搏是缓速心律失常的安全治疗方式，但据报道，0.6-3.5%的病例会发生严重的血栓形成和栓塞并发症。我们描述了5例起搏器相关血栓形成，3例伴有上腔静脉综合征（SVC）， 1例伴有腋窝静脉血栓形成，1例伴有右心房起搏导联的血栓。所有患者最初均以静脉注射肝素治疗，仅在最不严重的病例（腋窝静脉血栓形成）中，肝素是唯一成功的治疗方法。其中1例SVC梗阻患者经静脉肝素溶栓治疗成功。其余3例（2例SVC综合征和1例右心房血栓）需要手术切除血栓和起搏导联。两例有感染迹象的患者均属于药物治疗失败需要手术治疗的患者。版权所有(C) 2000 S. Karger AG，巴塞尔。
Although transvenous pacing is a safe treatment modality for bradyarrhythmias, serious thrombotic and embolic complications are reported to occur in 0.6-3.5% of cases, We describe 5 cases of pacemaker-associated thrombosis, 3 with a superior vena cava syndrome (SVC), 1 with an axillary vein thrombosis and 1 with a thrombus attached to the pacing lead in the right atrium, All of the patients were initially treated with intravenous heparin which proved successful as the sole treatment in only the least severe case (axillary vein thrombosis). One of the patients with SVC obstruction was successfully treated with intravenous heparin followed by thrombolytic therapy. The remaining 3 cases (2 SVC syndromes and 1 right atrial thrombus) required surgical removal of thrombus and pacing leads. Both of the patients with evidence of infection were in the group for whom failure of medical therapy necessitated surgery. Copyright (C) 2000 S. Karger AG, Basel.