Anaphylaxis to the chlorhexidine component of Instillagel®: a case series
Anaphylaxis to the chlorhexidine component of Instillagel®: a case series
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DOI：
10.1093/bja/aen324
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发表时间：
2009-01-01
影响因子：
9.8
通讯作者：
Pumphrey, R.
中科院分区：
文献类型：
--
作者：
Parkes, A. W.;Harper, N.;Pumphrey, R.
对氯己定过敏反应是罕见的。我们报告三例过敏反应归因于氯己定成分的Instillagel (R)，呈现后泌尿外科手术，而病人是在恢复室。在这些情况下，崩溃的原因并不立即明显，因为演示被推迟了。麻醉师应注意尿道润滑剂中可能含有氯己定，可引起易感个体的过敏反应。当病人在恢复室昏倒时，应将过敏反应视为一种可能的诊断。对与麻醉有关的疑似过敏反应进行调查，对于尝试和确定可能引发反应的因素，并帮助防止进一步接触和潜在危害非常重要。
Anaphylaxis to chlorhexidine is rare. We report three cases of anaphylaxis attributed to the chlorhexidine component of Instillagel (R), presenting after urological surgery, while the patients were in the recovery room. In these cases, the cause of the collapse was not immediately obvious as the presentation was delayed. Anaesthetists should be aware that urethral lubricants may contain chlorhexidine that can trigger anaphylaxis in susceptible individuals. Anaphylaxis should be considered a possible diagnosis when a patient collapses in the recovery room. Investigation of suspected anaphylactic reactions related to anaesthesia is important to try and identify a likely trigger for a reaction and to help prevent further exposure and potential harm.