ONTOGENY OF EYEBLINK CONDITIONING IN THE RAT - AUDITORY FREQUENCY AND DISCRIMINATION-LEARNING EFFECTS
ONTOGENY OF EYEBLINK CONDITIONING IN THE RAT - AUDITORY FREQUENCY AND DISCRIMINATION-LEARNING EFFECTS
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DOI：
10.1002/dev.420280602
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发表时间：
1995-09-01
影响因子：
2.2
通讯作者：
STANTON, ME
中科院分区：
文献类型：
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作者：
ANDREWS, SJ;FREEMAN, JH;STANTON, ME
本研究旨在确定听觉条件刺激（CS）的声学特性或辨别学习程序的使用是否会改变大鼠出生后第17天至24天（第17-24天）之间眨眼条件反射的出现。在实验1中，我们采用了3 × 2 × 2析因设计，涉及听觉CS的音高（2.8、5.0和9.0 kHz）、训练条件（配对与未配对）和年龄（第17或24天）。在第24天的所有音调频率下，联想学习都很明显，但在第17天的频率上有所增加，尽管在所有音调频率下，条件反射存在较大的年龄差异。在实验2中，训练幼鼠在第17天或第24天辨别2.8与9.0 kHz音调。眨眼条件反射在第24天随音调频率增加而增加，但在第17天没有出现辨别性条件反射。这些研究结果进行了讨论有关的作用，听觉系统的成熟在个体发育的眨眼条件。(C)1995年，John Wiley and Sons，Inc.
The present study sought to determine whether acoustic properties of the auditory conditioned stimulus (CS) or the use of a discrimination learning procedure would alter the emergence of eyeblink conditioning between postnatal Days 17 and 24 (Days 17-24) in the rat. In Experiment 1, we employed a 3 x 2 x 2 factorial design, involving pitch of the auditory CS (2.8, 5.0, and 9.0 kHz), training condition (paired vs. unpaired), and age (Days 17 or 24). Associative learning was evident at all tone frequencies on Day 24, but increased across frequencies on Day 17, although large age differences in conditioning remained at all tone frequencies. In Experiment 2, rat pups were trained to discriminate 2.8 versus 9.0-kHz tones on Day 17 or Day 24. Eyeblink conditioning increased with tone frequency on Day 24 but discriminative conditioning failed to appear on Day 17. These findings are discussed in relation to the role of auditory system maturation in the ontogeny of eyeblink conditioning. (C) 1995 John Wiley and Sons, Inc.