Mechanism of diarrhea of villous adenomas.
Mechanism of diarrhea of villous adenomas.
复制标题
绒毛状腺瘤腹泻的机制。
DOI：
10.1016/0002-9610(68)90030-5
复制
发表时间：
1968
影响因子：
3
通讯作者：
G. Peskin
中科院分区：
文献类型：
--
作者：
G. DaCruz;F. J. Gardner;G. Peskin
1.1.进行了一项研究，以确定绒毛状腺瘤提取物对体外结肠吸收液体和电解质的影响。2.2．使用外翻的肠囊，注意到绒毛状肿瘤抑制钠、钾、氯和液体穿过大鼠结肠壁的净转移。3.3。此外，通过测量钠（Na22）穿过结肠壁的双向通量，证明该离子净转移的减少是由于浆膜至粘膜成分的增加所致。4.4．这些结果与与人类某些绒毛状腺瘤相关的水电解耗竭综合征相关进行讨论。
1.1. A study was carried out to determine the influence of villous adenoma extracts on in vitro colonic absorption of fluid and electrolytes.2.2. Employing everted gut sacs, it was noted that villous tumor inhibited the net transfer of sodium, potassium, chloride, and fluid across the colon wall of the rat.3.3. Furthermore, by measuring the bidirectional flux of sodium (Na22) across the colonic wall, it was demonstrated that the diminution of net transfer of this ion resulted from an increase in the serosal to mucosal component.4.4. These results are discussed in relation to the hydroelectrolytic depletion syndrome associated with some villous adenomas in man.