Thymus-derived lymphocyte enumeration in patients with uveal malignant melanoma.
Thymus-derived lymphocyte enumeration in patients with uveal malignant melanoma.
复制标题
葡萄膜恶性黑色素瘤患者胸腺来源的淋巴细胞计数。
DOI：
10.1136/bjo.68.7.486
复制
发表时间：
1984
期刊：
影响因子：
--
通讯作者：
Shields,JA
中科院分区：
文献类型：
--
作者：
Felberg,NT;Shields,JA
Thymus-derived lymphocytes (T lymphocytes) were enumerated in patients with uveal malignant melanoma. Two T-lymphocyte subpopulations were determined, the active rosette forming cells (A-RFC) and the total rosette forming cells (T-RFC). Subjects were divided into the following groups: (a) pretreatment patients, (b) patients treated by enucleation, (c) patients treated by photocoagulation, (d) patients treated by cobalt plaque radiotherapy, (e) patients treated by enucleation who developed clinically detectable metastasis, and (f) normal controls. There were no differences in the numbers of A-RFC or T-RFC in the control population, pretreatment patients, and those treated in the different ways. Statistically significant depressions of A-RFC and T-RFC levels were seen in patients with metastatic lesions, suggesting that they had an impairment of immunocompetence, as measured by T-lymphocyte rosette formation.
