Scale-up of HIV treatment through PEPFAR: a historic public health achievement.
Scale-up of HIV treatment through PEPFAR: a historic public health achievement.
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DOI：
10.1097/qai.0b013e31825eb27b
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发表时间：
2012-08-15
期刊：
影响因子：
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通讯作者：
Whiteside A
中科院分区：
文献类型：
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作者：
El-Sadr WM;Holmes CB;Mugyenyi P;Thirumurthy H;Ellerbrock T;Ferris R;Sanne I;Asiimwe A;Hirnschall G;Nkambule RN;Stabinski L;Affrunti M;Teasdale C;Zulu I;Whiteside A
自2003年成立以来，美国总统艾滋病紧急救援计划(PEPFAR)一直是全球扩大艾滋病毒护理和治疗服务的重要推动力，特别是在扩大获得抗逆转录病毒治疗方面。尽管最初对成本和可行性感到担忧，但PEPFAR通过利用和协调其他资助者，通过与受影响最严重的国家合作，通过支持地方所有权，通过使用公共卫生方法，通过支持任务转移战略，以及通过关注加强卫生系统，克服了挑战。截至2011年9月，防治艾滋病紧急救援计划直接支持390万人开始抗逆转录病毒治疗，并为近1300万人提供护理和支助。那些接受服务的人在预防发病率和死亡率方面获得了好处，有证据表明，社会效益超出了预期的临床效益。然而，在实现普及、提高方案质量、确保患者留住护理以及继续加强卫生系统方面，仍有许多工作要做。
Since its inception in 2003, the US President’s Emergency Plan for AIDS Relief (PEPFAR) has been an important driving force behind the global scale-up of HIV care and treatment services, particularly in expansion of access to antiretroviral therapy. Despite initial concerns about cost and feasibility, PEPFAR overcame challenges by leveraging and coordinating with other funders, by working in partnership with the most affected countries, by supporting local ownership, by using a public health approach, by supporting task-shifting strategies, and by paying attention to health systems strengthening. As of September 2011, PEPFAR directly supported initiation of antiretroviral therapy for 3.9 million people and provided care and support for nearly 13 million people. Benefits in terms of prevention of morbidity and mortality have been reaped by those receiving the services, with evidence of societal benefits beyond the anticipated clinical benefits. However, much remains to be accomplished to achieve universal access, to enhance the quality of programs, to ensure retention of patients in care, and to continue to strengthen health systems.