GLUCOSE METABOLIC PATHWAYS IN THE ANAEROBIC RUMEN FUNGUS NEOCALLIMASTIX-FRONTALIS EB188
GLUCOSE METABOLIC PATHWAYS IN THE ANAEROBIC RUMEN FUNGUS NEOCALLIMASTIX-FRONTALIS EB188
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DOI：
10.1042/bj2740595
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发表时间：
1991-03-01
影响因子：
4.1
通讯作者：
CALZA, RE
中科院分区：
文献类型：
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作者：
OFALLON, JV;WRIGHT, RW;CALZA, RE
在厌氧瘤胃真菌Neocallimastix frontalis EB 188中建立了葡萄糖代谢的主要途径。 这种高能力的纤维素分解微生物表现出严格的厌氧代谢途径的整合。 糖酵解在N.额肌EB 188与苹果酸脱氢酶、“苹果酸”酶和特定的氢酶体反应偶联。 丙酮酸，和大多数生命形式一样，是一种关键化合物。 N.额肌EB 188的主要代谢产物为乙酸盐、乙醇和乳酸盐，并伴随产生H2。 根据其独特的特性和简化的发酵途径，可以得出结论，N。 额肌EB 188应该是从目前难以处理的生物质中产生能量和选定化学品的计划的重要贡献者。
Primary pathways for glucose metabolism were established in the anaerobic rumen fungus Neocallimastix frontalis EB188. This highly capable cellulolytic organism demonstrated a strict anaerobic integration of metabolic pathways. Glycolysis in N. frontalis EB188 was coupled to malate dehydrogenase, 'malic' enzyme and specified hydrogenosome reactions. Pyruvate, as in most life forms, was a pivotal compound. The major fermentation products of N. frontalis EB188 were acetate, ethanol and lactate, with the concomitant generation of H2. On the basis of its unique characteristics and streamlined fermentation pathways, it was concluded that N. frontalis EB188 should be an important contributor to programs generating energy and selected chemicals from currently intractable biomass.