Curcuma and Scutellaria plant extracts protect chickens against inflammation and Salmonella Enteritidis infection.
Curcuma and Scutellaria plant extracts protect chickens against inflammation and Salmonella Enteritidis infection.
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DOI：
10.3382/ps/pev190
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发表时间：
2015-09
期刊：
影响因子：
4.4
通讯作者：
Karolína Varmužová;M. Matulova;L. Geržová;Darina Čejková;D. Gardan‐Salmon;M. Panhéleux;F. Robert;F. Sisak;H. Havlíčková;I. Rychlík
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文献类型：
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作者：
Karolína Varmužová;M. Matulova;L. Geržová;Darina Čejková;D. Gardan‐Salmon;M. Panhéleux;F. Robert;F. Sisak;H. Havlíčková;I. Rychlík
在2006年欧盟禁止使用抗生素作为农场动物的生长促进剂之后，对具有抗菌或抗炎特性的替代产品的兴趣有所增加。因此，在本研究中，我们测试了姜黄和黄芩提取物作为饲料添加剂对热应激或沙门氏菌引起的盲肠炎症的影响。鸡的肠道感染。单独的姜黄提取物不足以减少热应激诱导的肠道炎症。然而，姜黄和紫藤提取物的混合物用作饲料添加剂可降低由热或S.肠道菌群减少。盲肠肠道菌群计数，但对BW或体液免疫应答无负面影响。使用下一代16S rRNA测序，我们发现用这两种植物提取物补充饲料对微生物群多样性没有影响。然而，如果向感染S.肠杆菌属、粪杆菌属和乳杆菌属，这两种已知对肠道健康具有积极影响的细菌属被积极选择。因此，在鸡饲料中补充姜黄和姜黄提取物可用于家禽生产，以有效降低肠道炎症并提高鸡的生产性能。
After a ban on the use of antibiotics as growth promoters in farm animals in the European Union in 2006, an interest in alternative products with antibacterial or anti-inflammatory properties has increased. In this study, we therefore tested the effects of extracts from Curcuma longa and Scutellaria baicalensis used as feed additives against cecal inflammation induced by heat stress or Salmonella Enteritidis (S. Enteritidis) infection in chickens. Curcuma extract alone was not enough to decrease gut inflammation induced by heat stress. However, a mixture of Curcuma and Scutellaria extracts used as feed additives decreased gut inflammation induced by heat or S. Enteritidis, decreased S. Enteritidis counts in the cecum but was of no negative effect on BW or humoral immune response. Using next-generation sequencing of 16S rRNA we found out that supplementation of feed with the 2 plant extracts had no effect on microbiota diversity. However, if the plant extract supplementation was provided to the chickens infected with S. Enteritidis, Faecalibacterium, and Lactobacillus, both bacterial genera with known positive effects on gut health were positively selected. The supplementation of chicken feed with extracts from Curcuma and Scutelleria thus may be used in poultry production to effectively decrease gut inflammation and increase chicken performance.