Occurrence and Biological Effects of Endocrine Disrupting Chemicals in the Yellow River (Zhengzhou Section)
Occurrence and Biological Effects of Endocrine Disrupting Chemicals in the Yellow River (Zhengzhou Section)
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黄河（郑州段）内分泌干扰物的赋存及生物效应
DOI：
10.1007/s00128-016-1930-4
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发表时间：
2016-12-01
影响因子：
2.7
通讯作者：
Wang, Zhi Jun
中科院分区：
文献类型：
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作者：
Song, Wen Ting;Wang, Zhi Jun
评估了黄河（郑州段）四个代表性断面河水的雌激素活性及其对鱼类繁殖和发育的影响。 MVLN检测结果显示，伊洛河、新蟒河、沁河和花园口断面河水雌二醇当量分别为1.09±0.11、0.72±0.01、1.19±0.19和0.80±0.04 ng/L。在接触伊洛河和沁河断面的河水 30 天后，成年雄性日本 Madaka (Oryzias latipes) 观察到显着的卵黄蛋白原 (VTG) 诱导 (p< 0.05)。接触沁河断面水的鱼肝体指数显着升高（p< 0.05）。在用新芒河断面的水处理的胚胎中观察到孵化时间显着延迟（p<0.05）。经过伊洛河和新芒河断面水处理的鱼在完全生命周期暴露后，存活率显着降低（p< 0.05）。伊洛河和沁河断面的水暴露导致第一条性成熟雄鱼的 VTG 水平显着升高（p< 0.05）。体外和体内生物测定均表明黄河（郑州段）存在内分泌干扰化学物质，伊洛河和沁河断面的鱼类可能面临生殖和发育障碍的风险。
Estrogenic activities of river water from four representative cross-sections of the Yellow River (Zhengzhou section) and their effects on reproduction and development of fish were assessed. MVLN assay showed estradiol equivalents of river water from Yiluohe, Xinmanghe, Qinhe and Huayuankou cross-sections were 1.09 ± 0.11, 0.72 ± 0.01, 1.19 ± 0.19 and 0.80 ± 0.04 ng/L, respectively. Significant vitellogenin (VTG) inductions were observed in adult male Japanese madaka (Oryzias latipes) after 30 days of exposure to river water from Yiluohe and Qinhe cross-sections (p< 0.05). Hepatic-somatic index was significantly elevated in fish exposed to water from Qinhe cross-section (p< 0.05). A significant delay in time to hatching was observed in embryos treated by water from Xinmanghe cross-section (p< 0.05). Significant lower survivals were observed in fish treated by water from Yiluohe and Xinmanghe cross-sections after a full life cycle exposure (p< 0.05). Exposure of water from Yiluohe and Qinhe cross-sections induced significantly elevated VTG levels in the first sexually mature male fish (p< 0.05). Both the in vitro and in vivo bioassay demonstrate endocrine disrupting chemicals exist in the Yellow River (Zhengzhou section) and fish in Yiluohe and Qinhe cross-sections can be at a risk of reproductive and developmental impairment.