Survival after pathological fractures of the proximal femur
Survival after pathological fractures of the proximal femur
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DOI：
10.5301/hip.2011.8654
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发表时间：
2011-09-01
影响因子：
1.5
通讯作者：
Rowlands, Tom K.
中科院分区：
文献类型：
--
作者：
Parker, Martyn J.;Khan, Asif Z.;Rowlands, Tom K.
我们报告了145例股骨近端病理性转移性骨折患者的生存情况。唯一存活的患者随访17.7年。死亡的144名患者的平均生存期为332天（范围为2至3053天），骨髓瘤（662天）、淋巴瘤（> 633天）和乳腺肿瘤（477天）最长，肺肿瘤（110天）最短。原发性肿瘤最常见的部位是乳腺（36%）、前列腺（23%）和肺（17%）。47%的骨折发生在关节囊内，28%发生在转子内，25%发生在转子下。99%的骨折患者接受了手术治疗，平均住院时间为19天。最常见的骨折愈合并发症是9/144（6.2%）例手术后发生的植入物周围或下方股骨进一步骨折。与原发肿瘤部位相关的患者生存率差异在计划手术治疗和与患者讨论预后方面具有相关性。
We report on the survival of 145 patients presenting to a single centre with a pathological metastatic fracture of the proximal femur. The single surviving patient had a follow-up of 17.7 years. Mean survival for the 144 patients who died was 332 days (range 2 to 3053 days), being longest for those with myeloma (662 days), lymphoma (> 633 days) and breast tumours (477 days) and lowest for lung tumours (110 days). The most common sites for the primary tumour were breast (36%), prostate (23%) and lung (17%). 47% of fractures were intracapsular, 28% trochanteric and 25% subtrochanteric. 99% of the fractures were treated surgically with a mean hospital stay of 19 days. The commonest fracture healing complication was further fracture of the femur around or immediately below the implant which occurred after 9/144 (6.2%) of operations. The difference in survival of patients related to the primary tumour site is of relevance in planning surgical treatment and discussing prognosis with patients.