Atherosclerosis: an integrative East-west medicine perspective.
Atherosclerosis: an integrative East-west medicine perspective.
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动脉粥样硬化：东西方医学的综合视角
DOI：
10.1155/2012/148413
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发表时间：
2012
期刊：
影响因子：
--
通讯作者：
Chen K
中科院分区：
文献类型：
--
作者：
Xu H;Shi D;Chen K
近年来对动脉粥样硬化和冠心病的认识已从管腔狭窄转向易损斑块，从脂质存款转向炎症反应，从易损斑块转向易损患者。这导致了一个新的治疗方向，包括干预炎症反应，稳定易损斑块，抑制斑块破裂后的血栓形成，治疗易损患者而不是治疗管腔狭窄。这似乎反映了中国传统医学（TCM）的重点是预防和治疗与使用中草药多靶点方法的模式功能障碍和失调相匹配的脆弱患者。鉴于东西方对动脉粥样硬化的概念趋同，东西方一体化的方法有望促进冠心病脆弱患者的早期发现和更有效的治疗。
Recent understanding of atherosclerosis and coronary heart disease has shifted the focus from lumen stenosis to vulnerable plaque, from lipid deposit to inflammatory reaction, and from vulnerable plaque to vulnerable patient. This has led to a new direction of treatment consisting of intervening the inflammatory reaction, stabilizing the vulnerable plaque, inhibiting thrombosis after plaque rupture, and treating the vulnerable patient instead of treating lumen stenosis. This seems to mirror the traditional Chinese medicine (TCM) focus on prevention and on the vulnerable patient with treatment matched to the pattern dysfunction and dysregulation using the Chinese herbal medicine multitargeted approach. Given the convergence of both the East and the West conceptualization of atherosclerosis, it is hopeful that the integrative East-West approach will facilitate early detection and more effective treatment of the vulnerable patients with coronary heart disease.