Surveillance of cardiovascular diseases using a multivariate dynamic screening system

Surveillance of cardiovascular diseases using a multivariate dynamic screening system
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使用多变量动态筛查系统监测心血管疾病

DOI:
10.1002/sim.6477
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发表时间:
2015-06
影响因子:
2
通讯作者:
Dongdong Xiang
Dongdong Xiang
中科院分区:
医学3区
文献类型:
--
作者:
Peihua Qiu;Dongdong Xiang

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在国家心脏、肺和血液研究所的SHARe心脏研究中,一项主要任务是监测几个健康变量(例如,血压和胆固醇水平),以便它们的不规则纵向模式可以被尽快地检测到并且一些医学治疗被及时地应用以避免一些致命的心血管疾病(例如,中风)。为了有效地处理这类应用,我们提出了一种新的统计方法称为多元动态筛选系统(MDySS)在本文中。MDySS方法结合了多变量纵向数据分析和多变量统计过程控制的主要优势,并且通过将其与其他受试者进行横截面比较并通过顺序监测来确定受试者的纵向模式。数值研究表明,MDySS在实际应用中效果良好.版权所有© 2015约翰威利父子有限公司.
In the SHARe Framingham Heart Study of the National Heart, Lung and Blood Institute, one major task is to monitor several health variables (e.g., blood pressure and cholesterol level) so that their irregular longitudinal pattern can be detected as soon as possible and some medical treatments applied in a timely manner to avoid some deadly cardiovascular diseases (e.g., stroke). To handle this kind of applications effectively, we propose a new statistical methodology called multivariate dynamic screening system (MDySS) in this paper. The MDySS method combines the major strengths of the multivariate longitudinal data analysis and the multivariate statistical process control, and it makes decisions about the longitudinal pattern of a subject by comparing it with other subjects cross sectionally and by sequentially monitoring it as well. Numerical studies show that MDySS works well in practice. Copyright © 2015 John Wiley & Sons, Ltd.
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