Impact of botulinum toxin injections on quality of life and self-esteem in patients with blepharospasm
Impact of botulinum toxin injections on quality of life and self-esteem in patients with blepharospasm
复制标题
肉毒毒素注射对眼睑痉挛患者生活质量和自尊的影响
DOI：
10.1080/13548506.2018.1549740
复制
发表时间：
2019-05-28
影响因子：
3.8
通讯作者：
Liu, Ping
中科院分区：
文献类型：
--
作者：
Tang, Min;Li, Wu;Liu, Ping
为了解A型肉毒毒素(BONT-A)注射对眼睑痉挛患者自尊和生活质量的影响，我们对87例患者进行了研究。患者在入选治疗前和接受ONT-A治疗4周后完成WHOQOL-BREF问卷、自尊量表(SES)和眼表疾病指数(OSDI)。治疗后患者的总体生活质量、一般健康状况、WHOQOL-BREF的生理和心理领域评分、社会支持量表评分均有明显改善。治疗后运动症状改善，OSDI评分增加。总体生活质量和SES评分与病程相关，而心理领域评分与平均疗效持续时间相关。所有变量均与OSDI评分相关。总之，BoNT-A注射改善了眼睑痉挛患者的生活质量和自尊。
ABSTRACT To determine the effects of botulinum toxin type A (BoNT-A) injections on self-esteem and quality of life (QOL) in blepharospasm patients, we enrolled 87 patients into the study. Patients completed the WHOQOL-BREF questionnaire, the Self-Esteem Scale (SES), and the Ocular Surface Disease Index (OSDI) before treatment on the date of enrollment and again after 4 weeks of treatment with BoNT-A. The overall QOL, general health status, the physiological and psychological domain scores of the WHOQOL-BREF, and the SES score significantly improved after treatment. The motor symptoms improved, and the OSDI score increased after treatment. Overall QOL and SES scores were correlated with disease duration, while psychological domain scores were correlated with mean duration of therapeutic effect. All variables correlated with OSDI scores. In conclusion, BoNT-A injections improved QOL and self-esteem in blepharospasm patients.