Implementation of a blood irradiation program at a community cancer center
Implementation of a blood irradiation program at a community cancer center
复制标题
DOI：
10.1046/j.1537-2995.2001.41121610.x
复制
发表时间：
2001-12-01
期刊：
影响因子：
2.9
通讯作者：
Skowronski, MG
中科院分区：
文献类型：
--
作者：
Patton, GA;Skowronski, MG
背景：成分血照射是预防输血相关GVHD的公认方法。以前的出版物主要集中在辐照过程本身的技术方面，但相对较少关注与社区癌症中心水平的血液辐照计划的实施相关的细节。研究设计和方法：进行了一项观察性研究，详细说明了具体的操作、记录，以及在社区癌症中心的机构范围内提供血液成分辐照服务所采用的质量保证措施。蒙哥马利癌症中心在1998年和1999年辐照了589个单位的血液成分，为当地血库提供了一种采购辐照血液成分的替代方案，同时符合适用的质量保证和法规要求。结论：血液成分照射是在大多数设备精良和人员充足的社区癌症中心的范围内。血液成分辐照计划的建立需要科学物理学和剂量测定支持，以确保辐照成分的质量并满足政府机构的监管要求。
BACKGROUND: Blood component irradiation is an accepted method of preventing transfusion-associated GVHD. Previous publications have largely focused on the technical aspects of the irradiation process itself, but relatively little attention has been paid to the details associated with the implementation of a blood irradiation program at the level of a community cancer center.STUDY DESIGN AND METHODS: An observational study was performed, detailing the specific operational, documentation, and quality assurance measures employed in providing a blood component-irradiation service within the institutional context of a community cancer center.RESULTS: The Montgomery Cancer Center irradiated 589 units of blood components in 1998 and 1999 to provide a local blood bank with an alternative for procurement of irradiated blood components while complying with applicable quality assurance and regulatory requirements.CONCLUSION: Blood component irradiation is within the scope of most well-equipped and adequately staffed community cancer centers. Establishment of a blood component irradiation program requires scrupulous physics and dosimetry support, both to ensure the quality of the irradiated component and to satisfy governmental agency regulatory requirements.