The Synaptic Organization of the Brain
The Synaptic Organization of the Brain
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DOI：
10.1001/jama.1980.03300440052037
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发表时间：
1980-05
期刊：
影响因子：
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通讯作者：
F. Freemon
中科院分区：
文献类型：
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作者：
F. Freemon
这本书的第一版调和了突触生理学与经典神经元理论的新发现。对于像海马体或小脑这样的大脑区域，谢泼德描述了主要神经元，说明了它们之间的突触相互关系，并绘制了一个“基本回路”。这第二版扩展到包括其他大脑区域，如基底神经节，并传达新的发现，特别是关于神经递质物质。与传统观点相反，对于某些大脑区域，树突而不是整个神经元才是基本的信息处理单元。树突汇总突触对其的影响，并通过树突突触将处理后的输入传递给另一个树突，而不一定影响神经元细胞体或轴突膜上的电位。事实上，对于嗅球的颗粒细胞和视网膜的无突细胞来说，树突动作是唯一可以发生的神经元交流；这些细胞没有轴突。
The first edition of this book reconciled new findings in synaptic physiology with classic neuron theory. For each of several brain regions such as hippocampus or cerebellum, Shepherd described the major neurons, illustrated their synaptic interrelationships, and diagramed a "basic circuit." This second edition expands to include other brain regions such as the basal ganglia and to communicate new findings, especially regarding neurotransmitter substances. For some brain regions, contrary to the classic view, the dendrite rather than the entire neuron is the basic information-processing unit. The dendrite summates synaptic influences on it and, by way of dendrodendritic synapses, transfers this processed input to another dendrite, without necessarily affecting the potential on the neuronal cell body or axonal membrane. In fact, for the granule cell of the olfactory bulb and the amacrine cell of the retina, dendrodendritic action is the only neuronal communication that can occur; these cells have no axons.