Clonazepam and Botulinum Toxin for the Treatment of Alien Limb Phenomenon
Clonazepam and Botulinum Toxin for the Treatment of Alien Limb Phenomenon
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DOI：
10.1097/nrl.0b013e3181a0d670
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发表时间：
2010-03-01
期刊：
影响因子：
1.2
通讯作者：
Rodriguez, Ramon R.
中科院分区：
文献类型：
--
作者：
Haq, Ihtsham U.;Malaty, Irene A.;Rodriguez, Ramon R.
我们讨论一个病人谁开发了“外星人的肢体”在她的右侧脑疝后。她报告说，她感觉自己的手臂运动好像是由一个陌生人控制的，并表现出肢体漂浮和摸索行为。患者接受0.5 mg氯硝西泮b.i.d.治疗。其次是肢体悬浮频率降低73%。停用氯硝西泮和重审证实了这一反应。她患有精神病发作，她归因于氯硝西泮。停用氯硝西泮。她接受了肉毒杆菌毒素注射到她的手臂，减少了84%的肢体悬浮。这是第一次报告的反应，药物治疗异肢综合征。
We discuss a patient who developed an "alien limb" on her right side after brain herniation. She reported feeling as though her arm movements were controlled by a stranger and displayed limb levitation and groping behaviors. She received 0.5 mg clonazepam b.i.d. This was followed by a limb levitation frequency reduction of 73%. Discontinuation and retrial of clonazepam verified this response. She suffered a psychotic episode that she attributed to clonazepam. Clonazepam was discontinued. She received botulinum toxin injections to her arm that reduced her limb levitation by 84%. This is the first report of response to medication in alien limb syndrome.