Diagnosis of residual Descemet's membrane after Descemet's stripping endothelial keratoplasty with anterior segment optical coherence tomography

Diagnosis of residual Descemet's membrane after Descemet's stripping endothelial keratoplasty with anterior segment optical coherence tomography
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DOI:
10.1016/j.jcrs.2007.03.029
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发表时间:
2007-07-01
影响因子:
2.8
通讯作者:
Yoo, Sonia H.
Yoo, Sonia H.
中科院分区:
医学2区
文献类型:
--
作者:
Kymionis, George D.;Suh, Leejee H.;Yoo, Sonia H.

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我们介绍了一名在后弹力层剥离内皮角膜移植术 (DSEK) 后通过眼前段光学相干断层扫描 (AS-OCT) 诊断出后弹力层残留的患者。术后观察到持续的部分角膜水肿和界面积液,没有供体纽扣脱位。随访期间未发现界面液有改善。 4 个月内诊断出初次供体移植失败,并通过穿透性角膜移植术对患者进行了重新移植。标本的病理学检查显示受者角膜纽扣中存在残留的后弹力层,经 AS-OCT 成像证实。该病例报告表明,接受者按钮中后弹力层剥离不充分可能是 DSEK 失败的潜在原因; AS-OCT 是一种有用的非侵入性仪器,用于诊断和监测这种 DSEK 后并发症。
We present a patient with residual Descemet's membrane diagnosed by anterior segment optical coherence tomography (AS-OCT) after Descemet's stripping endothelial keratoplasty (DSEK). Postoperatively, persistent partial corneal edema and interface fluid without dislocation of the donor button were observed. No improvement of interface fluid was found during the follow-up period. A primary donor graft failure was diagnosed within 4 months, and the patient was regrafted with penetrating keratoplasty. Pathology examination of the specimen revealed the presence of residual Descemet's membrane in the recipient corneal button, confirmed using AS-OCT imaging. This case report demonstrates that inadequate Descemet's stripping in the recipient button could be a potential cause of DSEK failure; AS-OCT is a useful and noninvasive instrument for diagnosing and monitoring this post-DSEK complication.