PREDICTING BIOAVAILABILITY OF PAHS AND PCBS WITH POREWATER CONCENTRATIONS MEASURED BY SOLID-PHASE MICROEXTRACTION FIBERS
PREDICTING BIOAVAILABILITY OF PAHS AND PCBS WITH POREWATER CONCENTRATIONS MEASURED BY SOLID-PHASE MICROEXTRACTION FIBERS
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DOI：
10.1002/etc.495
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发表时间：
2011-05-01
影响因子：
4.1
通讯作者：
Reible, Danny D.
中科院分区：
文献类型：
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作者：
Lu, Xiaoxia;Skwarski, Alison;Reible, Danny D.
在暴露于Anacostia河（华盛顿特区，美国）和Brown湖（维克斯堡，美国）的最初未受污染的沉积物中28 d，随后用3 - 25%受污染的新贝德福德港沉积物（新贝德福德，马萨诸塞州，美国）稀释的沉积物中，测定了沉积物摄食寡食藻Ilyodrilus templetoni的多环芳烃（PAHs）和多氯联苯（PCBs）的生物积累。阿纳科斯蒂亚河沉积物研究代表了暴露于历史上受污染的沉积物中，但可用性有限，而暴露于其他沉积物包括历史上受污染的新贝德福德港沉积物和重新分配到布朗湖沉积物中的污染物。生物组织浓度与阿纳科斯蒂亚河沉积物中的大块沉积物浓度无关，但与顺序稀释的沉积物相关。然而，通过一次性固相微萃取纤维（SPME）和聚二甲基硅氧烷（PDMS）测量的孔隙水浓度与所有沉积物中的生物吸收率相关良好。孔隙水浓度与复合辛醇水分分配系数的乘积呈良好的线性关系(Anacostia，斜率= 1.08,r(2) = 0.76；顺序稀释沉积物，斜率= 1.24,r(2) = 0.76)。数据表明，辛醇水分配系数是脂质水分配系数的良好指标，孔隙水浓度比沉积物浓度提供了更可靠的生物积累指标，即使摄取途径预计是通过沉积物摄入。环绕。Toxicol。化学2011;30:1109 - 1116。(c) 2011年第6集
Bioaccumulation of polycyclic aromatic hydrocarbons (PAHs) and polychlorinated biphenyls (PCBs) was measured in the deposit-feeding oligochaete Ilyodrilus templetoni exposed for 28 d to Anacostia River sediment (Washington, DC, USA) and to an initially uncontaminated sediment from Brown Lake (Vicksburg, MS, USA) sequentially diluted with 3 to 25% contaminated New Bedford Harbor sediment (New Bedford, MA, USA). The Anacostia River sediment studies represented exposure to a historically contaminated sediment with limited availability, whereas exposure to the other sediment included both the historically contaminated New Bedford Harbor sediment and fresh redistribution of contaminants into the Brown Lake sediments. Organism tissue concentrations did not correlate with bulk sediment concentrations in the Anacostia River sediment but did correlate with the sequentially diluted sediment. Porewater concentrations measured via disposable solid-phase microextraction fiber (SPME) with polydimethylsiloxane (PDMS), however, correlated well with organism uptake in all sediments. Bioaccumulation was predicted well by a linear relationship with the product of porewater concentration and compound octanol water partition coefficient (Anacostia, slope = 1.08, r(2) = 0.76; sequentially diluted sediments, slope = 1.24, r(2) = 0.76). The data demonstrate that the octanol water partition coefficient is a good indicator of the lipid water partition coefficient and that porewater concentrations provide a more reliable indicator of bioaccumulation in the organism than sediment concentrations, even when the route of uptake is expected to be via sediment ingestion. Environ. Toxicol. Chem. 2011;30:1109-1116. (C) 2011 SETAC