Cochlear hair cell loss in ears with cholesteatomas. Scanning electron microscopy study.
Cochlear hair cell loss in ears with cholesteatomas. Scanning electron microscopy study.
复制标题
患有胆脂瘤的耳朵中的耳蜗毛细胞丢失。
DOI：
10.1177/000348948809700113
复制
发表时间：
1988
期刊：
影响因子：
--
通讯作者：
Chiu,M
中科院分区：
文献类型：
--
作者：
Chole,RA;Chiu,M
Cochleas from 16 Mongolian gerbils with spontaneous aural cholesteatomas, and four of similar age without cholesteatomas, were examined by scanning electron microscopy to quantify cochlear hair cell loss. Loss of hair cell stereocilia was found in all ears with cholesteatomas and was increased when compared with uninvolved ears from animals of similar age. The hair cell loss assorted with gerbilline cholesteatomas appeared to be most marked in the middle turn of the cochlea and increased in severity with increasing size of the cholesteatomas. Outer hair cells were affected more than inner hair cells. Inner and outer hair cell loss was not significantly different infected cholesteatomas versus sterile cholesteatomas. The greater damage to hair cels at the middle turn compared to the basal turn suggests that these losses may be the result of some agent acting through the cochlear wall rather than through the round window.
