Determinants of cough in young adults participating in the European Community Respiratory Health Survey
Determinants of cough in young adults participating in the European Community Respiratory Health Survey
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DOI：
10.1183/09031936.01.00098701
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发表时间：
2001-10-01
影响因子：
24.3
通讯作者：
Burney, P
中科院分区：
文献类型：
--
作者：
Janson, C;Chinn, S;Burney, P
咳嗽是一种常见的症状，影响了很大一部分普通人群。本调查的目的是确定来自不同国家的人群样本中夜间、非生产性和生产性咳嗽的决定因素。在一项横断面国际人口调查中，来自16个国家的18,277名受试者（20-48岁）回答了一份以访谈为主导的问卷。测定总免疫球蛋白e和特异性免疫球蛋白e，并进行肺活量测定。定义了三种类型的咳嗽：夜间咳嗽、非生产性咳嗽和生产性咳嗽。独立变量与咳嗽的关系通过每个中心或国家的逻辑回归来估计，并通过随机效应荟萃分析在各个中心或国家进行组合。不同中心夜间咳嗽、非生产性咳嗽和生产性咳嗽的中位患病率分别为30.7%、10.2%和10.2%。夜间咳嗽和非生产性咳嗽与女性相关（调整比值比（OR）分别为2.08和1.27），夜间咳嗽和生产性咳嗽与鼻炎相关（OR分别为1.46和1.61）。这三种类型的咳嗽都与哮喘、吸烟、环境吸烟和肥胖有关。女性比男性更有可能报告夜间和非生产性咳嗽。咳嗽与可治疗的疾病有关，如哮喘和鼻炎，以及可避免的疾病。因素，如吸烟和环境烟草烟雾。
Cough is a common symptom that affects a large proportion of the general population. The aim of this investigation was to identify determinants of nocturnal, nonproductive and productive cough in population samples from different countries.In a cross-sectional international population survey, 18,277 subjects (20-48 yrs) from 16 countries answered an interview-led questionnaire. Total and specific immunoglobulin-E was measured and spirometry was performed. Three types of cough were defined: nocturnal, nonproductive and productive cough. The relation of the independent variables to cough was estimated by means of logistic regression for each centre or country and combined across centre or country by random-effects meta-analysis.The median prevalence of nocturnal, nonproductive and productive cough in the different centres was 30.7%, 10.2% and 10.2%, respectively. Nocturnal and nonproductive cough were related to female sex (adjusted odds ratio (OR)=2.08 and 1.27, respectively), while nocturnal and productive cough were related to rhinitis (OR=1.46 and 1.61, respectively). All three types of cough were related to asthma, tobacco smoking, environmental tobacco smoke and obesity.Females are more likely to report nocturnal and nonproductive cough than males. Cough was related to treatable disorders, like asthma and rhinitis, as well a avoidable. factors, such as tobacco smoking and environmental tobacco smoke.