Reading performance in children with rolandic epilepsy correlates with nocturnal epileptiform activity, but not with epileptiform activity while awake
Reading performance in children with rolandic epilepsy correlates with nocturnal epileptiform activity, but not with epileptiform activity while awake
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DOI：
10.1016/j.yebeh.2011.08.008
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发表时间：
2011-11-01
影响因子：
2.6
通讯作者：
Aldenkamp, A. P.
中科院分区：
文献类型：
--
作者：
Ebus, S. C. M.;Overvliet, G. M.;Aldenkamp, A. P.
目的：经常有报道称语言障碍与罗兰癫痫之间存在关联。这种损害可能与夜间癫痫样活动量相关。方法：我们回顾性分析了 26 名患有罗兰性癫痫和/或罗兰性棘波的儿童。所有患者均在两周内接受了 24 小时脑电图和神经心理学评估。测量阅读表现（阅读单词和句子）和智力。结果：夜间癫痫样活动量与阅读句子之间存在显着负相关关系R = -0.525（P = 0.008）。阅读单词的这种相关性有 R = -0.398 (P = 0.054) 的趋势。我们发现夜间癫痫样活动量与言语智商之间呈负相关（R = -0.51 P = 0.08）。阅读表现或言语智商与昼间癫痫样活动量之间没有发现相关性。结论：罗兰癫痫儿童的阅读表现受损，并且与夜间癫痫样活动量相关。 (C) 2011 Elsevier Inc. 保留所有权利。
Objective: An association between language impairment and rolandic epilepsy is frequently reported. This impairment could be correlated with the amount of nocturnal epileptiform activity.Methods: We retrospectively analyzed 26 children with rolandic epilepsy and/or rolandic spikes. All had undergone a 24-hour EEG and neuropsychological assessment within 2 weeks. Reading performance (reading words and sentences) and intelligence were measured.Results: There was a significant negative correlation between amount of nocturnal epileptiform activity and reading sentences R = -0.525 (P = 0.008). There was a trend in this correlation for reading words R = -0.398 (P = 0.054). We found a negative correlation between amount of nocturnal epileptiform activity and Verbal IQ (R = -0.51 P = 0.08). No correlation was found between reading performance or Verbal IQ and amount of diurnal epileptiform activity.Conclusions: Reading performance is impaired in children with rolandic epilepsy and is correlated with the amount of nocturnal epileptiform activity. (C) 2011 Elsevier Inc. All rights reserved.