INFLUENCE OF ETIOLOGY OF ATRIAL-FIBRILLATION ON INCIDENCE OF SYSTEMIC EMBOLISM
INFLUENCE OF ETIOLOGY OF ATRIAL-FIBRILLATION ON INCIDENCE OF SYSTEMIC EMBOLISM
复制标题
DOI：
10.1016/0002-9149(77)90064-9
复制
发表时间：
1977-01-01
影响因子：
2.8
通讯作者：
FISHER, CM
中科院分区：
文献类型：
--
作者：
HINTON, RC;KISTLER, JP;FISHER, CM
众所周知，房颤会大大增加二尖瓣疾病患者的全身动脉栓塞风险。针对其他类型心脏病房颤患者栓塞的临床发生率，对333例不同类型心脏病房颤尸检患者的栓塞情况进行了分析。仅考虑经病理或手术证实的症状性栓塞，二尖瓣疾病患者中有41%发生栓塞，缺血性心脏病患者中有35%发生栓塞，二尖瓣和缺血性心脏病并存患者中有35%发生栓塞，“其他”类型心脏病患者中有17%发生栓塞。在对照组的58例无房颤的缺血性心脏病尸检患者中，只有7%的人发现栓塞。这些发现表明，任何原因的房颤都有很高的栓塞风险，尤其是缺血性心脏病和二尖瓣疾病引起的房颤。
Atrial fibrillation is well known to increase greatly the risk of systemic arterial embolism in patients with mitral valve disease. In light of the clinical frequency of embolism in patients with atrial fibrillation due to other types of heart disease, a study was made of embolic occurrences in 333 autopsy patients with atrial fibrillation associated with various kinds of heart disease. Considering only symptomatic emboli with pathologic or surgical confirmation, embolism occurred in 41 percent of patients with mitral valve disease, 35 percent of those with ischemic heart disease, 35 percent of those with coexisting mitral and ischemic heart disease and 17 percent of those with “other” types of heart disease. Embolism was found in only 7 percent of a control group of 58 autopsy patients with ischemic heart disease without atrial fibrillation. These findings suggest a high risk of embolism from atrial fibrillation of any origin, but particularly from that caused by ischemic heart disease and mitral valve disease.