SEVERE ILLNESS WITH INFLUENZA-B

SEVERE ILLNESS WITH INFLUENZA-B
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DOI:
10.1016/0002-9343(80)90352-6
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发表时间:
1980-01-01
影响因子:
5.9
通讯作者:
MARTIN, SM
MARTIN, SM
中科院分区:
医学2区
文献类型:
--
作者:
BAINE, WB;LUBY, JP;MARTIN, SM

文献摘要

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在1977年的前11周内,近期感染B型流感的患者(15例)在3家达拉斯[德克萨斯州,美国]医院住院。患者年龄范围为4-73岁,中位数为18岁。大多数没有明显的基础疾病。临床疾病谱包括流感后细菌性肺炎(3例)、其他严重胸部疾病(2例)、高热和老年人可能的横纹肌溶解症(2例)、妊娠毒血症发作、甲状腺功能障碍、Stevens-Johnson综合征、神经系统疾病(2例)和Reye综合征(3例)。两名患者死亡。2例高热、乏力的老年男性在发病3天内入院,3例Reye综合征患者中有2例在流感发病4天后入院,但其他11例患者在住院前有7-31天的症状史。B型流感的发病率和死亡率既不是微不足道的,也不限于虚弱的宿主。
Patients (15) with recent influenza B infection were admitted to 3 Dallas [Texas, USA] hospitals in the first 11 wk of 1977. The patients'' ages ranged from 4-73 yr with a median of 18 yr. Most had no significant underlying disease. The spectrum of clinical illness included post-influenzal bacterial pneumonia (3 cases), other severe chest disease (2 cases), hyperpyrexia and possible rhabdomyolysis in the elderly (2 cases), onset of toxemia of pregnancy, thyroid dysfunction, Stevens-Johnson syndrome, neurologic disorders (2 cases) and Reye''s syndrome (3 cases). Two patients died. Two elderly men with high fever and weakness entered the hospital within 3 days of illness and 2 of 3 patients with Reye''s syndrome were admitted 4 days after the onset of influenza, but the 11 other patients gave a history of 7-31 days of symptoms before being hospitalized. Morbidity and mortality with influenza B are neither trivial nor restricted to debilitated hosts.